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Advanced filters: Author: Kristyna Cunatova Clear advanced filters

Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners

Here, the authors investigate the maturation of human respiratory Complex II, uncovering two metastable intermediates of maturation which suggest changes in intrinsic disorder ensure that the assembly steps occur in the correct sequence.

Pankaj Sharma
Elena Maklashina
T. M. Iverson
ResearchOpen Access11 Jan 2024
Nature Communications

Volume: 15, P: 1-15
Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome

Detailed characterization of mtDNA haplotypes uncovers the impact of mitochondrial rRNA variations on mitochondrial translation and oxidative capacity and their metabolic consequences including insulin resistance development induced by high-fat diet.

Petr Pecina
Kristýna Čunátová
Alena Pecinová
ResearchOpen Access11 Sept 2024
Communications Biology

Volume: 7, P: 1-17
Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia

Dora Ravasz
David Bui
Christos Chinopoulos
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-21