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SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation

The lncRNA SAMMSON promotes a balanced increase in rRNA maturation and protein synthesis in the cytosol and mitochondria by modulating the localization of CARF, which affects two rRNA-processing factors.

Roberto Vendramin
Yvessa Verheyden
Eleonora Leucci
Research29 Oct 2018
Nature Structural & Molecular Biology

Volume: 25, P: 1035-1046

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SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation

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