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Showing 1–6 of 6 results

Advanced filters: Author: Kuninori Suzuki Clear advanced filters

Phase separation organizes the site of autophagosome formation

The pre-autophagosomal structure in yeast is a liquid-like condensate of Atg proteins whose phase separation may have a critical, active role in autophagy.

Yuko Fujioka
Jahangir Md. Alam
Nobuo N. Noda
Research05 Feb 2020
Nature

Volume: 578, P: 301-305
Atg2 mediates direct lipid transfer between membranes for autophagosome formation

Structural and biochemical data suggest that the essential autophagy protein Atg2 acts as a lipid-transfer protein that supplies phospholipids from the source organelle (especially the ER) to the isolation membranes (IMs) for autophagosome formation.

Takuo Osawa
Tetsuya Kotani
Nobuo N. Noda
Research25 Mar 2019
Nature Structural & Molecular Biology

Volume: 26, P: 281-288
Dynamics and diversity in autophagy mechanisms: lessons from yeast

Studies of autophagy in yeast have identified a family of autophagy-related (Atg) proteins, which are required for membrane formation in autophagy. The dynamic assembly of Atg proteins into the pre-autophagosomal structure dictates the localization and activity of the autophagic machinery.

Hitoshi Nakatogawa
Kuninori Suzuki
Yoshinori Ohsumi
Reviews03 Jun 2009
Nature Reviews Molecular Cell Biology

Volume: 10, P: 458-467
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Selective autophagy in budding yeast

Kuninori Suzuki
ReviewsOpen Access15 Jun 2012
Cell Death & Differentiation

Volume: 20, P: 43-48
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14