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Inhibition of hepatitis B virus in mice by RNA interference

Anton P McCaffrey
Hiroyuki Nakai
Mark A Kay
Research12 May 2003
Nature Biotechnology

Volume: 21, P: 639-644
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

Many short hairpin RNAs (shRNAs) are toxic when expressed in mice — this is traced to possible competition between the shRNAs and endogenous microRNAs for binding to exportin-5, a factor involved in transporting molecules out of the nucleus.

Dirk Grimm
Konrad L. Streetz
Mark A. Kay
Research25 May 2006
Nature

Volume: 441, P: 537-541
Assessment of leaf morphological, physiological, chemical and stoichiometry functional traits for understanding the functioning of Himalayan temperate forest ecosystem

Monika Rawat
Kusum Arunachalam
Rajiv Pandey
ResearchOpen Access10 Dec 2021
Scientific Reports

Volume: 11, P: 1-10