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Showing 1–2 of 2 results
Advanced filters: Author: Kwang-Min Yu Clear advanced filters

  • Here, Kim et al. characterize SARS-CoV-2 infection in juvenile, young, and old aged ferrets to provide a further understanding of differences in COVID-19 severity in humans at different ages. Aged ferrets have higher viral loads, shed virus longer, and mimic the transcriptomic profile of severely infected patients.

    • Young-Il Kim
    • Kwang-Min Yu
    • Young Ki Choi
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Therapies and vaccines for COVID-19, caused by the SARS-CoV-2 viral pandemic, are urgently needed. Here the authors establish and screen an antibody library from a convalescent COVID-19 patient to isolate a neutralizing antibody with the ability to reduce viral titer and alleviate symptoms in ferret, hamster, and rhesus monkey infection models.

    • Cheolmin Kim
    • Dong-Kyun Ryu
    • Soo-Young Lee
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10