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Showing 1–6 of 6 results
Advanced filters: Author: Kymberlie Hallsworth Pepin Clear advanced filters
  • Makedonka Mitreva and colleagues report the genome sequence and transcriptome analysis of the hookworm Necator americanus, a prevalent soil-transmitted human parasite and the cause of necatoriasis. They develop a hookworm protein microarray to examine the host parasite interaction and immune response, tested on blood samples from 200 individuals in an endemic region.

    • Yat T Tang
    • Xin Gao
    • Makedonka Mitreva
    ResearchOpen Access
    Nature Genetics
    Volume: 46, P: 261-269
  • A genomic comparison of 27 global isolates of Onchocerca volvulus, the agent of river blindness, elucidates its evolutionary history and reveals ancestry informative loci that can differentiate between forest, savanna and admixed isolates.

    • Young-Jun Choi
    • Rahul Tyagi
    • Makedonka Mitreva
    Research
    Nature Microbiology
    Volume: 2, P: 1-10
  • The Human Microbiome Project Consortium has established a population-scale framework to study a variety of microbial communities that exist throughout the human body, enabling the generation of a range of quality-controlled data as well as community resources.

    • Barbara A. Methé
    • Karen E. Nelson
    • Owen White
    ResearchOpen Access
    Nature
    Volume: 486, P: 215-221
  • The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

    • Curtis Huttenhower
    • Dirk Gevers
    • Owen White
    ResearchOpen Access
    Nature
    Volume: 486, P: 207-214
  • Comparative study of 81 genomes of parasitic and non-parasitic worms identifies gene family births and expanded gene families at key nodes in the phylogeny that are relevant to parasitism and proteins historically targeted for drug development.

    • Avril Coghlan
    • Rahul Tyagi
    • Matthew Berriman
    ResearchOpen Access
    Nature Genetics
    Volume: 51, P: 163-174