Sporulation in diderm Firmicutes requires the remodeling of an inner membrane into a functional outer membrane. Uncharacterized to date, this process involves the complete replacement of all proteins and lipids within a membrane. Here, the authors present a model in which the self-insertion of BamA triggers the inner-to-outer membrane remodeling.
- Polina Beskrovnaya
- Ameena Hashimi
- Elitza I. Tocheva
