Jeremy Linsley, Atmiyata Tripathi et al. optimise culturing techniques and develop a microscopy platform and that can automatically image and track single neurons within organotypic slices for up to a three-week period. Using a model of polyQ neurodegeneration, they show that this method can assess longitudinal cell changes with high accuracy.
- Jeremy W. Linsley
- Atmiyata Tripathi
- Steven Finkbeiner
