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Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model

Roseburia intestinalis is a butyrate-producing member of the gut microbiome that can use dietary plant polysaccharides to alter host metabolism, transcription and epigenetics, and lower inflammation and endotoxaemia, resulting in reduced atherosclerosis.

Kazuyuki Kasahara
Kimberly A. Krautkramer
Federico E. Rey
Research05 Nov 2018
Nature Microbiology

Volume: 3, P: 1461-1471
Atherosclerosis: Scavenger cell receptor shared

Michael S. Brown
Joseph L. Goldstein
News & Views22 Aug 1985
Nature

Volume: 316, P: 680-681
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function

Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.

L. Grevendonk
N. J. Connell
J. Hoeks
ResearchOpen Access06 Aug 2021
Nature Communications

Volume: 12, P: 1-17
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

Brown adipose tissue (BAT) produces heat by burning lipid triglycerides. Here, Berbée et al. show that pharmacological BAT activation protects hyperlipidemic mice from atherosclerosis, provided mice retain the metabolic capacity to clear cholesterol-enriched lipoprotein remnants by the liver.

Jimmy F. P. Berbée
Mariëtte R Boon
Patrick C.N. Rensen
ResearchOpen Access10 Mar 2015
Nature Communications

Volume: 6, P: 1-11
Meiosis in haploid rye: extensive synapsis and low chiasma frequency

J L Santos
M M Jiménez
M Díez
Research01 Dec 1994
Heredity

Volume: 73, P: 580-588
High prevalence of occult paragangliomas in asymptomatic carriers of SDHD and SDHB gene mutations

Berdine L Heesterman
Jean Pierre Bayley
Jeroen C Jansen
Research05 Sept 2012
European Journal of Human Genetics

Volume: 21, P: 469-470
Clinical progression and metachronous paragangliomas in a large cohort of SDHD germline variant carriers

Berdine L Heesterman
Lisa M H de Pont
Jeroen C Jansen
Research18 May 2018
European Journal of Human Genetics

Volume: 26, P: 1339-1347
The effect of dietary phytosphingosine on cholesterol levels and insulin sensitivity in subjects with the metabolic syndrome

M Snel
M A Sleddering
I M Jazet
Research24 Feb 2010
European Journal of Clinical Nutrition

Volume: 64, P: 419-423
Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols

R Korpela
J Tuomilehto
M J Tikkanen
Research11 Jan 2006
European Journal of Clinical Nutrition

Volume: 60, P: 633-642
Maternal apolipoprotein E genotype as a potential risk factor for poor birth outcomes: The Bogalusa Heart Study

M B Jacobs
E W Harville
W Chen
Research18 Feb 2016
Journal of Perinatology

Volume: 36, P: 432-438
Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death

L S M Boesten
S M Zadelaar
J-C Marine
Research26 May 2006
Cell Death & Differentiation

Volume: 13, P: 2089-2098
Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation

Wen Liang
Jan H Lindeman
Robert Kleemann
Research24 Feb 2014
Laboratory Investigation

Volume: 94, P: 491-502

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Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model

Atherosclerosis: Scavenger cell receptor shared

Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

Meiosis in haploid rye: extensive synapsis and low chiasma frequency

High prevalence of occult paragangliomas in asymptomatic carriers of SDHD and SDHB gene mutations

Clinical progression and metachronous paragangliomas in a large cohort of SDHD germline variant carriers

The effect of dietary phytosphingosine on cholesterol levels and insulin sensitivity in subjects with the metabolic syndrome

Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols

Maternal apolipoprotein E genotype as a potential risk factor for poor birth outcomes: The Bogalusa Heart Study

Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death

Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation

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