Even after complete resection of nonmetastatic pancreatic cancer, recurrence rates are high. Combined modality therapy including radiation therapy reduces the recurrence rate and improves disease-free survival for several types of tumor of the gastrointestinal tract, but the use of adjuvant radiotherapy for pancreatic cancer is controversial. In this Review, the authors discuss the studies—prospective and retrospective—and the issues surrounding the use of adjuvant radiotherapy for pancreatic cancer.
- Ruchika Gutt
- Stanley L Liauw
- Ralph R Weichselbaum
