Hepatocellular carcinoma is a global health problem, although developing countries are disproportionally affected. About three-quarters of hepatocellular carcinomas are attributed to chronic HBV and HCV infections. This Review provides an overview of the global variation in hepatocellular carcinoma incidence and etiology, as well as the prevention, screening, diagnosis and treatment of this cancer.
- Ju Dong Yang
- Lewis R. Roberts