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Showing 1–6 of 6 results

Advanced filters: Author: Lacey Douthit Clear advanced filters

Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells

The tumour-targeting activity and specificity of T cells with a CAR forming a reversible covalent bond with a hapten can be regulated by a small-molecule adapter that selectively binds to the hapten and to a chosen tumour antigen.

Alexey V. Stepanov
Jia Xie
Richard A. Lerner
Research05 Oct 2023
Nature Biomedical Engineering

Volume: 8, P: 529-543
Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

Glycan molecules can be modified directly on the cell surface via chemoenzymatic approaches. Here, the authors employ a set of four bacterial glycosyltransferases to develop a live cell-based killing assay to probe host cell glycan-mediated influenza A virus infection.

Senlian Hong
Yujie Shi
Peng Wu
ResearchOpen Access17 Apr 2019
Nature Communications

Volume: 10, P: 1-11
Structures of the intermediates of Kok’s photosynthetic water oxidation clock

Crystallography and spectroscopy are used to solve high-resolution structures of the intermediates of Kok’s S-state clock in photosystem II.

Jan Kern
Ruchira Chatterjee
Vittal K. Yachandra
Research07 Nov 2018
Nature

Volume: 563, P: 421-425
Structure of photosystem II and substrate binding at room temperature

The structures of three intermediate states of photosystem II, which is crucial for photosynthesis, have been solved at room temperature, shedding new light on this process.

Iris D. Young
Mohamed Ibrahim
Junko Yano
Research21 Nov 2016
Nature

Volume: 540, P: 453-457
Correction: Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies

Jinqi Huang
Stepanov Alexey
Chi-Meng Tzeng
Amendments and Corrections16 May 2019
Leukemia

Volume: 33, P: 2341
Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies

Jinqi Huang
Stepanov Alexey
Chi-Meng Tzeng
Research08 Apr 2019
Leukemia

Volume: 33, P: 2315-2319