Cerebral cavernous malformations (CCMs) are clusters of dilated capillaries affecting around 0.5% of the population. The authors analyzed the phenotypic characteristics of chronic and acute murine models of CCM. The acute model harbored higher lesion burden while the chronic model showed more inflammation and lesional iron deposition.
- Hussein A. Zeineddine
- Romuald Girard
- Issam A. Awad