Innate lymphoid cells (ILC) are an important modulator of immunity in many tissues, including lymphoid tissues, but their spatial information is still scarce. Here, the authors use multiplexed and multispectral imaging methods to provide a spatial map of ILCs in human thymus, spleen, lymph nodes, intestinal lymphoid tissue, and lymphoma, and observe ILC/T helper cells colocalization.
- Nathalie Van Acker
- François-Xavier Frenois
- Pierre Brousset