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Advanced filters: Author: Lauriane Ramet Clear advanced filters

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1^−/− mice

In mice lacking PINK1, bacterial infection in the intestine results in mitochondrial antigen presentation and generation of CD8⁺ T cells, and infected mice develop motor impairments, suggesting that PINK1 suppresses autoimmunity.

Diana Matheoud
Tyler Cannon
Michel Desjardins
Research17 Jul 2019
Nature

Volume: 571, P: 565-569
Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

Odile Poirel
Sébastien Mella
Salah El Mestikawy
ResearchOpen Access17 Jan 2018
Scientific Reports

Volume: 8, P: 1-14

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Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice

Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

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Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1^−/− mice