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Showing 1–10 of 10 results
Advanced filters: Author: Laurie E. Comstock Clear advanced filters

  • Bacteroides strains have multiple operons for biosynthesis of diverse capsular polysaccharides, but most cells express only one operon at a time due to tight regulation of transcription elongation by locus-specific UpxY and UpxZ proteins. Here, Saba et al. provide insight into the mechanisms by which UpxY distinguishes among cognate operons and how UpxZ inhibits only noncognate UpxY proteins.

    • Jason Saba
    • Katia Flores
    • Robert Landick
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Bacteria often produce antimicrobial toxins to compete in microbial communities. Here, the authors identify a family of peptide toxins that are produced by, and target, Bacteroidetes species, some of which are widespread in the human gut microbiota.

    • Michael J. Coyne
    • Nathalie Béchon
    • Laurie E. Comstock
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • The bacterium Phocaeicola vulgatus is commonly found in the human gut. Here, the authors show that the microorganism produces an antibacterial toxin that targets the LPS core glycan of closely related species and induces a response that partially protects cells from multiple antimicrobial toxins.

    • Jordan C. Evans
    • Valentina Laclare McEneany
    • Laurie E. Comstock
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Game theory has contributed much to the understanding of social evolution. In an elegant combination of experimental tests and modelling, this study suggests that when bacteria face intense competition, repeated retaliation outcompetes a single tit-for-tat response to attack.

    • William P. J. Smith
    • Maj Brodmann
    • Kevin R. Foster
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • The human intestine is home to trillions of bacteria. Investigation of the colonization of the infant gut by these microorganisms is a prelude to understanding how they may act in both health and disease.

    • Laurie E. Comstock
    News & Views
    Nature
    Volume: 448, P: 542-544

  • A study finds that the cells lining the gut are modified in response to systemic infection, increasing the host's tolerance to infection in a manner that is dependent on the microorganisms that inhabit the gut. See Letter p.638

    • Seth Rakoff-Nahoum
    • Laurie E. Comstock
    News & Views
    Nature
    Volume: 514, P: 576-577

  • Little is known about cooperative behaviour among the gut microbiota; here, limited cooperation is demonstrated for Bacteroides thetaiotaomicron, but Bacteroides ovatus is found to extracellularly digest a polysaccharide not for its own use, but to cooperatively feed other species such as Bacteroides vulgatus from which it receives return benefits.

    • Seth Rakoff-Nahoum
    • Kevin R. Foster
    • Laurie E. Comstock
    Research
    Nature
    Volume: 533, P: 255-259