Nature Search

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Richard Karlsson Linnér
Travis T. Mallard
Danielle M. Dick
Amendments and Corrections06 Dec 2024
Nature Neuroscience

Volume: 28, P: 213
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

This paper identified >500 genetic loci associated with behaviors and disorders related to self-regulation, including addiction and child behavior problems. The resulting genetic risk scores predict several behavioral, medical and social outcomes.

Richard Karlsson Linnér
Travis T. Mallard
Danielle M. Dick
Research26 Aug 2021
Nature Neuroscience

Volume: 24, P: 1367-1376
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans

Dongbing Lai
Tae-Hwi Schwantes-An
Tatiana Foroud
ResearchOpen Access05 Jul 2022
Translational Psychiatry

Volume: 12, P: 1-7
Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

Renato Polimanti
Raymond K. Walters
Joel Gelernter
Research26 Feb 2020
Molecular Psychiatry

Volume: 25, P: 1673-1687
Genome-wide association study of stimulant dependence

Jiayi Cox
Richard Sherva
Lindsay A. Farrer
ResearchOpen Access29 Jun 2021
Translational Psychiatry

Volume: 11, P: 1-10
Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

Peter B. Barr
Albert Ksinan
Danielle M. Dick
ResearchOpen Access18 Jun 2020
Translational Psychiatry

Volume: 10, P: 1-9
A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior

Jacquelyn L. Meyers
Jian Zhang
Bernice Porjesz
Research20 May 2020
Molecular Psychiatry

Volume: 26, P: 5040-5052
Psychosocial moderation of polygenic risk for cannabis involvement: the role of trauma exposure and frequency of religious service attendance

Jacquelyn L. Meyers
Jessica E. Salvatore
Arpana Agrawal
ResearchOpen Access21 Oct 2019
Translational Psychiatry

Volume: 9, P: 1-12
Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders

Hye M. Hwang
Satoshi Yamashita
Kazue Hashimoto-Torii
ResearchOpen Access11 May 2024
Molecular Psychiatry

Volume: 29, P: 3364-3380
Readiness for Parkinson’s disease genetic testing and counseling in patients and their relatives in urban settings in the Dominican Republic

Margaret Hackl
Lola Cook
Priscila Delgado Hodges
ResearchOpen Access29 Aug 2023
npj Parkinson's Disease

Volume: 9, P: 1-8
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Nathan Gaddis
Ravi Mathur
Eric Otto Johnson
ResearchOpen Access07 Oct 2022
Scientific Reports

Volume: 12, P: 1-16
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

A. Mesut Erzurumluoglu
Mengzhen Liu
Joanna M. M. Howson
ResearchOpen Access07 Jan 2019
Molecular Psychiatry

Volume: 25, P: 2392-2409
Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

Peter B. Barr
Travis T. Mallard
Danielle M. Dick
ResearchOpen Access30 Sept 2022
Translational Psychiatry

Volume: 12, P: 1-8

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

Genome-wide association study of stimulant dependence

Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior

Psychosocial moderation of polygenic risk for cannabis involvement: the role of trauma exposure and frequency of religious service attendance

Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders

Readiness for Parkinson’s disease genetic testing and counseling in patients and their relatives in urban settings in the Dominican Republic

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

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