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Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters

Waning immunity and the emergence of the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness and required vaccine updates. Here, the authors assess how different priming regimens affect the immunogenicity of BA.1 and BA.5 bivalent boosters.

Luca M. Zaeck
Ngoc H. Tan
Rory D. de Vries
ResearchOpen Access18 May 2024
Nature Communications

Volume: 15, P: 1-12
Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals

Historic smallpox vaccination and monkeypox virus (MPXV) infection elicit MPXV-neutralizing antibodies, but MPXV-neutralizing antibodies are less frequent and of lower magnitude after vaccination with MVA-BN—the vaccine approved and in use for protection against MPXV and smallpox.

Luca M. Zaeck
Mart M. Lamers
Rory D. de Vries
ResearchOpen Access18 Oct 2022
Nature Medicine

Volume: 29, P: 270-278
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14

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