New insights into the mechanisms underlying atrial fibrillation have identified promising new approaches to prevent the fundamental processes that lead to the generation of arrhythmia. Dobrev and colleagues discuss the rationale for developing new anti-atrial fibrillation drugs, the molecular and structural motifs that they target, and the results obtained in experimental and clinical studies.
- Dobromir Dobrev
- Leif Carlsson
- Stanley Nattel
