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Showing 1–3 of 3 results
Advanced filters: Author: Lemonia Chatzeli Clear advanced filters

  • The authors show that the ramified ductal network of the mouse salivary gland develops from a set of simple probabilistic rules, where ductal elongation and branching are driven by the persistent expansion of the surrounding tissue.

    • Ignacio Bordeu
    • Lemonia Chatzeli
    • Benjamin D. Simons
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • By inducing changes in surrounding tissue, mutant intestinal stem cells create an unfavourable niche environment that gives them a competitive advantage over non-mutant neighbours.

    • Min Kyu Yum
    • Seungmin Han
    • Benjamin D. Simons
    Research
    Nature
    Volume: 594, P: 442-447

  • The cellular basis of islet morphogenesis and fate allocation remain unclear. Here, the authors use a R26-CreER-R26R-Confetti mouse line to follow quantitatively the clonal dynamics of islet formation showing how, during the secondary transition, islet progenitors amplify through rounds of stochastic cell division before becoming restricted to α and β cell sublineages.

    • Magdalena K. Sznurkowska
    • Edouard Hannezo
    • Benjamin D. Simons
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14