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Showing 1–2 of 2 results
Advanced filters: Author: Leszek Michalak Clear advanced filters
  • Here, the authors tailor an acetylated galactoglucomannan (AcGGM) fibre from spruce wood to specifically enrich Roseburia and Faecalibacterium - beneficial species which have the enzymatic machinery to breakdown the fibre and generate butyrate. They subsequently perform a piglet feeding trial, metagenomics and metaproteomics, together showing that AcGGM-fed pigs exhibit not only increased Roseburia and Faecalibacterium populations with AcGGM-specific mannan-specific esterases, but also secondary metabolic pathways.

    • Leszek Michalak
    • John Christian Gaby
    • Bjørge Westereng
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15
  • How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, highlighting a potential for β-mannan-based therapeutic interventions.

    • Sabina Leanti La Rosa
    • Maria Louise Leth
    • Bjørge Westereng
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14