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Showing 1–2 of 2 results
Advanced filters: Author: Levi P. Sowers Clear advanced filters

  • Exposure to psychostimulants such as cocaine induces synaptic plasticity within the nucleus accumbens (NAc) and alters behavior. Here the authors find a new role for the acid-sensing channel 1A (ASIC1A) in excitatory transmission and plasticity within the NAc that contributes to cocaine-induced learning and self-administration.

    • Collin J Kreple
    • Yuan Lu
    • John A Wemmie
    Research
    Nature Neuroscience
    Volume: 17, P: 1083-1091

  • Sudden unexpected death in epilepsy (SUDEP) is cited as the cause of nearly 2,000 deaths per year in the USA alone, and accounts for as many as 15% of epilepsy-related deaths. Controversy prevails over the relative contributions of cardiac failure and respiratory arrest to SUDEP. Here, the authors discuss the mechanisms that cause cardiac, respiratory and arousal abnormalities during the ictal and postictal periods, and highlight possible preventive interventions that might reduce the risk of SUDEP.

    • Cory A. Massey
    • Levi P. Sowers
    • George B. Richerson
    Reviews
    Nature Reviews Neurology
    Volume: 10, P: 271-282