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Nature Cell Biology (1)

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Advanced filters: Author: Lidia Argemi-Muntadas Clear advanced filters

α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells

Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferase activity and the pluripotency network.

Karlien Van Nerum
Anne Wenzel
Jan Jakub Żylicz
ResearchOpen Access23 Apr 2025
Nature Cell Biology

Volume: 27, P: 749-761

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α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells

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