Nature Search

Galectin-3-integrin α5β1 phase separation disrupted by advanced glycation end-products impairs diabetic wound healing in rodents

This study shows that Galectin-3 promotes wound healing by binding to and undergoing phase separation with integrin α5β1, a process disrupted by AGEs in pre-clinical models of diabetes. Topical Galectin-3 restored healing in synergy with insulin.

Zhongyu Zhang
Zhengde Zhao
Sifan Chen
ResearchOpen Access07 Aug 2025
Nature Communications

Volume: 16, P: 1-23
Low-frequency vibrational modes of stable glasses

The nature of the vibrational modes of amorphous solids is of fundamental interest, but assessing them is challenging due to very long equilibrium times involved. Wang et al. numerically model the localized low-frequency vibrational modes in glasses and show the sensitivity of their populations to glass stability.

Lijin Wang
Andrea Ninarello
Elijah Flenner
ResearchOpen Access03 Jan 2019
Nature Communications

Volume: 10, P: 1-7
Intermediate soil acidification induces highest nitrous oxide emissions

Intermediate soil acidification alters the denitrifier community composition and induces high nitrous oxide (N₂O) emissions, which contributes to the observed acceleration of N₂O emissions from global soils

Yunpeng Qiu
Yi Zhang
Shuijin Hu
ResearchOpen Access27 Mar 2024
Nature Communications

Volume: 15, P: 1-12
Low-frequency vibrational density of states of ordinary and ultra-stable glasses

Power-law scaling of low-frequency vibrational density of states is widely observed in glassy materials, yet the value of scaling exponents remains controversial. Here, Xu et al. identify two scaling exponents by separating stable from unstable glass to reconcile the debate in the literature.

Ding Xu
Shiyun Zhang
Ning Xu
ResearchOpen Access16 Feb 2024
Nature Communications

Volume: 15, P: 1-9
Correction: Corrigendum: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like

Seham Ebrahim
Matthew R. Avenarius
Bechara Kachar
Amendments and CorrectionsOpen Access14 Aug 2017
Nature Communications

Volume: 8, P: 1
Atomically precise Ni clusters inducing active NiN₂ sites with uniform-large vacancies towards efficient CO₂-to-CO conversion

Catalysts synthesized by current methods for CO₂ electroreduction to CO exhibit limited activity and selectivity over broad potentials. Here, the authors report an in situ etching method to create NiN₂ sites with uniform-large vacancies that achieve high activity across a wide potential window.

Guangyuan Xu
Xingjie Peng
Huan Yan
ResearchOpen Access22 Apr 2025
Nature Communications

Volume: 16, P: 1-13
Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

Genetic studies of Chinese individuals have been performed, but mostly with short read sequencing, limiting the types of variants that can be identified. Here, the authors perform long read sequencing of 945 han Chinese individuals, finding structural variants under natural selection and those associated with human traits and evolutionary history.

Jiao Gong
Huiru Sun
Shaohua Fan
ResearchOpen Access10 Feb 2025
Nature Communications

Volume: 16, P: 1-21
Genomic analyses reveal the stepwise domestication and genetic mechanism of curd biogenesis in cauliflower

A high-quality reference genome assembly of cauliflower C-8 (V2) and genomic analyses of 971 diverse accessions and their relatives reveal the stepwise domestication and the genetic mechanism of curd biogenesis.

Rui Chen
Ke Chen
Deling Sun
ResearchOpen Access07 May 2024
Nature Genetics

Volume: 56, P: 1235-1244
Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress

Thermogenic proteins like PGC1α are downregulated under thermal stress, but the underlying mechanisms are unclear. Here, the authors show that chaperone-mediated autophagy, regulated by PARK7, controls PGC1α stability and BAT function at thermoneutrality.

Yixiao Zhuang
Xinyi Zhang
Xingxing Kong
ResearchOpen Access14 May 2025
Nature Communications

Volume: 16, P: 1-16
3D-printed model-guided endoscopic evacuation for basal ganglia hemorrhage

Jun Zhang
Hongyu Cheng
Yuqian Li
ResearchOpen Access23 Mar 2020
Scientific Reports

Volume: 10, P: 1-7
Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii

Here the authors show an intermediate state of the photosystem II (PSII) repair cycle, where three protein factors and an α-tocopherol quinone molecule are associated with a damaged PSII at distinct sites, fulfilling their specific functions in the repair process.

Anjie Li
Tingting You
Zhenfeng Liu
ResearchOpen Access18 Jun 2024
Nature Communications

Volume: 15, P: 1-17
Landscape of pathogenic mutations in premature ovarian insufficiency

Whole-exome sequencing analyses in a cohort of 1,030 patients with premature ovarian insufficiency identify new likely pathogenic variants and reveal distinct genetic architectures between primary and secondary amenorrhea.

Hanni Ke
Shuyan Tang
Zi-Jiang Chen
ResearchOpen Access02 Feb 2023
Nature Medicine

Volume: 29, P: 483-492
Associations between testosterone and future PTSD symptoms among middle age and older UK residents

Hanyang Shen
Ciera Stafford
Laramie E. Duncan
ResearchOpen Access06 Aug 2025
Translational Psychiatry

Volume: 15, P: 1-9
Genetic variants underlying differences in facial morphology in East Asian and European populations

A genome-wide study based on three-dimensional facial images identifies new loci associated with facial morphology in East Asian populations. Comparison with data from European populations identifies variants related to facial shape differences between these populations.

Manfei Zhang
Sijie Wu
Sijia Wang
Research07 Apr 2022
Nature Genetics

Volume: 54, P: 403-411
Transition from Kwon [4+2]- to [3+2]-cycloaddition enabled by AgF-assisted phosphine catalysis

Phosphine catalysis generally relies on the potential of carbanion phosphonium zwitterions that are generated via nucleophilic addition of phosphine catalyst to electrophilic reactants. Here, the authors demonstrate that AgF can be used as additive to expand phosphine catalysis.

Jinlong Qian
Lijin Zhou
Xiaofeng Tong
ResearchOpen Access14 Aug 2024
Nature Communications

Volume: 15, P: 1-9
Perceived service quality mediates the effect of physical servicescape on tourists’ intention to stay in rural homestays

Yi Yang
Lijin Wang
Jiaqi Yan
ResearchOpen Access12 Aug 2025
Scientific Reports

Volume: 15, P: 1-12
A rapid aureochrome opto-switch enables diatom acclimation to dynamic light

Diatoms thrive in dynamic environments that frequently confer high light stress. In this study, the authors report a diatom photoreceptor that triggers immediate transcription of photoprotective genes upon high light signals. The fast response kinetics of this pathway confer advantages in environments with rapid light fluctuations.

Huan Zhang
Xiaofeng Xiong
Xiaobo Li
ResearchOpen Access03 Jul 2024
Nature Communications

Volume: 15, P: 1-18
First-line sugemalimab with chemotherapy for advanced esophageal squamous cell carcinoma: a randomized phase 3 study

In a prespecified interim analysis of the phase 3 trial GEMSTONE-304, anti-PD-L1 with chemotherapy versus chemotherapy alone led to significantly prolonged progression-free survival and overall survival of patients with unresectable, locally advanced, recurrent or metastatic esophageal squamous cell carcinoma.

Jin Li
Zhendong Chen
Jason Yang
Research01 Feb 2024
Nature Medicine

Volume: 30, P: 740-748
Structural basis for energy and electron transfer of the photosystem I–IsiA–flavodoxin supercomplex

Cyanobacterial photosystem I supercomplexes bind to iron-stress-induced proteins IsiA and flavodoxin under iron-deficiency conditions. They form a network that is highly efficient at light harvesting and retains normal electron transport efficiency.

Peng Cao
Duanfang Cao
Mei Li
Research10 Feb 2020
Nature Plants

Volume: 6, P: 167-176
Large-scale lexical and genetic alignment supports a hybrid model of Han Chinese demic and cultural diffusions

By digitizing a large lexical dataset of Chinese dialects and comparing it to genetic profiles, Yang et al. reveal a hybrid model of language diffusion, consisting of both population migrations and social learning across different regions of China.

Chengkun Yang
Xiaoxi Zhang
Menghan Zhang
Research13 May 2024
Nature Human Behaviour

Volume: 8, P: 1163-1176
Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches

Breviscapine is the flavonoid extract from medical plant Erigeron breviscapus for the treatment of cardio- and cerebrovascular disease. Here, the authors identify the key enzymes of the biosynthetic pathway from the plant genome and engineer yeast to produce breviscapine from glucose.

Xiaonan Liu
Jian Cheng
Huifeng Jiang
ResearchOpen Access31 Jan 2018
Nature Communications

Volume: 9, P: 1-10
Decoupling between water use and thermoelectric power generation growth in China

Decoupling resource use from energy production is critical for sustainable development. Here, researchers show a decoupling between water use and electricity generation growth in China, accompanied by changing spatial distribution of associated water stress.

Chao Zhang
Lijin Zhong
Jiao Wang
Research10 Sept 2018
Nature Energy

Volume: 3, P: 792-799
SUNRED, a natural extract-based biostimulant, application stimulates anthocyanin production in the skins of grapes

Qunxian Deng
Hui Xia
Dong Liang
ResearchOpen Access22 Feb 2019
Scientific Reports

Volume: 9, P: 1-8
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test

Patients whose disease is diagnosed in its early stages have better outcomes. In this study, the authors develop a non invasive blood test based on circulating tumor DNA methylation that can potentially detect cancer occurrence even in asymptomatic patients.

Xingdong Chen
Jeffrey Gole
Li Jin
ResearchOpen Access21 Jul 2020
Nature Communications

Volume: 11, P: 1-10
A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds

Lijin Zou
Yonglun Luo
Cody Bünger
ResearchOpen Access22 Jul 2013
Scientific Reports

Volume: 3, P: 1-10
Inferring the Dynamics of Effective Population Size Using Autosomal Genomes

Zheng Hou
Yin Luo
Li Jin
ResearchOpen Access01 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Random Bits Forest: a Strong Classifier/Regressor for Big Data

Yi Wang
Yi Li
Li Jin
ResearchOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1-8
Indoor PM_2.5 exposure affects skin aging manifestation in a Chinese population

Anan Ding
Yajun Yang
Sijia Wang
ResearchOpen Access10 Nov 2017
Scientific Reports

Volume: 7, P: 1-7
Feasibility study on cardiac resynchronization in the treatment of heart failure by single left bundle branch pacing

Yadong Du
Lijin Pu
Ling Zhao
ResearchOpen Access14 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
Novel evaluation method based on critical arch height as instability criterion for sustaining arch locked-segment-type slopes

Lijin Wang
Hang Jia
Li Wan
ResearchOpen Access05 Apr 2024
Scientific Reports

Volume: 14, P: 1-20
HCDT 2.0: A Highly Confident Drug-Target Database for Experimentally Validated Genes, RNAs, and Pathways

Xinying Liu
Dehua Feng
Jin Li
ResearchOpen Access25 Apr 2025
Scientific Data

Volume: 12, P: 1-7
Nuclear Norm Clustering: a promising alternative method for clustering tasks

Yi Wang
Yi Li
Li Jin
ResearchOpen Access18 Jul 2018
Scientific Reports

Volume: 8, P: 1-7
Chromosome-scale genome assembly of a natural diploid kiwifruit (Actinidia chinensis var. deliciosa)

Hui Xia
Honghong Deng
Dong Liang
ResearchOpen Access14 Feb 2023
Scientific Data

Volume: 10, P: 1-9
Tillage practices and straw-returning methods affect topsoil bacterial community and organic C under a rice-wheat cropping system in central China

Lijin Guo
Shixue Zheng
Chengfang Li
ResearchOpen Access09 Sept 2016
Scientific Reports

Volume: 6, P: 1-10
Genome diversity of Chinese indigenous chicken and the selective signatures in Chinese gamecock chicken

Wei Luo
Chenglong Luo
Qinghua Nie
ResearchOpen Access03 Sept 2020
Scientific Reports

Volume: 10, P: 1-14
Adequate iodine nutrition and higher salt intake in Chinese adults aged 18–59 years recommended by international organizations

Diqun Chen
Ying Ye
Zhihui Chen
ResearchOpen Access24 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Interpretable machine learning for maximum corrosion depth and influence factor analysis

Yuhui Song
Qinying Wang
Yuchen Xi
ResearchOpen Access02 Feb 2023
npj Materials Degradation

Volume: 7, P: 1-15
Serplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial

Shukui Qin
Jin Li
Jun Zhu
ResearchOpen Access19 Oct 2022
British Journal of Cancer

Volume: 127, P: 2241-2248
Bagging Nearest-Neighbor Prediction independence Test: an efficient method for nonlinear dependence of two continuous variables

Yi Wang
Yi Li
Li Jin
ResearchOpen Access06 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans

Xiang-Hong Xu
Xue-Wen Huang
Jiucun Wang
ResearchOpen Access12 Dec 2014
Scientific Reports

Volume: 4, P: 1-8
Paleolithic Contingent in Modern Japanese: Estimation and Inference using Genome-wide Data

Yungang He
Wei R. Wang
Pan-Asia SNP Consortium
ResearchOpen Access05 Apr 2012
Scientific Reports

Volume: 2, P: 1-7
Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy

Bin Zhou
Hui Dong
Jinlin Hou
ResearchOpen Access24 Nov 2015
Scientific Reports

Volume: 5, P: 1-10
MtDNA analysis reveals enriched pathogenic mutations in Tibetan highlanders

Longli Kang
Hong-Xiang Zheng
Li Jin
ResearchOpen Access08 Aug 2016
Scientific Reports

Volume: 6, P: 1-11
CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity

Liliang Li
Pan Gao
Li Jin
ResearchOpen Access24 Jun 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-15
Fine population structure analysis method for genomes of many

Xuedong Pan
Yi Wang
Li Jin
ResearchOpen Access03 Oct 2017
Scientific Reports

Volume: 7, P: 1-9
Correction To: Serplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial

Shukui Qin
Jin Li
Jun Zhu
Amendments and CorrectionsOpen Access02 Nov 2022
British Journal of Cancer

Volume: 127, P: 2249

Search

Filter By:

Search

Quick links