Nature Search

Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer

Lymph nodes are primarily categorised into metastatic and non-metastatic. Here, the authors perform integrated bulk and single-cell RNA sequencing on lymph nodes from 200 patients with colorectal cancer and identify 4 non-metastatic lymph node subtypes.

Xu Guan
Yueyang Zhang
Xishan Wang
ResearchOpen Access22 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Homogeneous polymer-ionic solvate electrolyte with weak dipole-dipole interaction enabling long cycling pouch lithium metal battery

Solid polymer electrolytes suffer from limited ionic conductivity and poor interfacial stability for lithium batteries. Here, authors propose a fluorinated ether diluent to reduce the dipole-dipole interaction of ionic solvate with the polymer matrix and induce the formation of aggregates.

Likun Chen
Tian Gu
Feiyu Kang
ResearchOpen Access14 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Metal-organic double layer to stabilize selective multi-carbon electrosynthesis

Here the authors immobilize quaternary ammonium cations on the surface of Cu catalyst to suppress the carbonate precipitation, achieving a Faradaic efficiency of 50% for ethylene product at 200 mA/cm² from CO₂ electroreduction.

Jian Cheng
Ling Chen
Yang Peng
ResearchOpen Access21 Apr 2025
Nature Communications

Volume: 16, P: 1-15
Prognostic and predictive value of the newly proposed grading system of invasive pulmonary adenocarcinoma in Chinese patients: a retrospective multicohort study

Likun Hou
Tingting Wang
Xiaojie Pan
Research10 Jan 2022
Modern Pathology

Volume: 35, P: 749-756
Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Glucagon-like peptide 1 (GLP1) is processed and cleaved from proglucagon to stimulate insulin secretion. Here, authors show that Nogo-B interacts with proglucagon to retain it on the ER, thereby inhibiting PCSK1-mediated cleavage of proglucagon and secretion of GLP1.

Ke Gong
Chao Xue
Yajun Duan
ResearchOpen Access10 Aug 2024
Nature Communications

Volume: 15, P: 1-20
Publisher Correction: Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Ke Gong
Chao Xue
Yajun Duan
Amendments and CorrectionsOpen Access10 Sept 2024
Nature Communications

Volume: 15, P: 1
NEK6 dampens FOXO3 nuclear translocation to stabilize C-MYC and promotes subsequent de novo purine synthesis to support ovarian cancer chemoresistance

Jingchun Liu
Haoyu Wang
Li Hong
ResearchOpen Access10 Sept 2024
Cell Death & Disease

Volume: 15, P: 1-17
CXCR1⁺ neutrophil infiltration orchestrates response to third-generation EGFR-TKI in EGFR mutant non-small-cell lung cancer

Haowei Wang
Anwen Xiong
Tao Jiang
ResearchOpen Access06 Dec 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-15
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

Zhijian Xu
Danrong Shi
Weiliang Zhu
ResearchOpen Access24 Apr 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-8
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

Susu Qu
Xiangyu Zhou
Li Zhang
ResearchOpen Access13 Nov 2023
Molecular Psychiatry

Volume: 29, P: 165-185
Characterization of evolution trajectory and immune profiling of brain metastasis in lung adenocarcinoma

Tao Jiang
Yan Yan
Caicun Zhou
ResearchOpen Access12 Feb 2021
npj Precision Oncology

Volume: 5, P: 1-9
Erratum: An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)

Wenzhu Peng
Jian Xu
Peng Xu
Amendments and CorrectionsOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1
FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma

Jingchao Wang
Jue Jiang
Hudan Liu
Research12 Aug 2019
Oncogene

Volume: 38, P: 6737-6751
Targeting CDK7 increases the stability of Snail to promote the dissemination of colorectal cancer

Yan Zhou
Linlin Lu
Hongsheng Wang
Research19 Nov 2018
Cell Death & Differentiation

Volume: 26, P: 1442-1452
Down-regulation of GADD45A enhances chemosensitivity in melanoma

Jia Liu
Guoqiang Jiang
Weiling Li
ResearchOpen Access07 Mar 2018
Scientific Reports

Volume: 8, P: 1-11
Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms

Yuan Xu
Xian Liu
Mingyue Zheng
ResearchOpen Access02 Sept 2015
Scientific Reports

Volume: 5, P: 1-13
An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)

Wenzhu Peng
Jian Xu
Peng Xu
ResearchOpen Access26 May 2016
Scientific Reports

Volume: 6, P: 1-16

Search

Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer

Homogeneous polymer-ionic solvate electrolyte with weak dipole-dipole interaction enabling long cycling pouch lithium metal battery

Metal-organic double layer to stabilize selective multi-carbon electrosynthesis

Prognostic and predictive value of the newly proposed grading system of invasive pulmonary adenocarcinoma in Chinese patients: a retrospective multicohort study

Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Publisher Correction: Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

NEK6 dampens FOXO3 nuclear translocation to stabilize C-MYC and promotes subsequent de novo purine synthesis to support ovarian cancer chemoresistance

CXCR1⁺ neutrophil infiltration orchestrates response to third-generation EGFR-TKI in EGFR mutant non-small-cell lung cancer

Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

Characterization of evolution trajectory and immune profiling of brain metastasis in lung adenocarcinoma

Erratum: An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)

FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma

Targeting CDK7 increases the stability of Snail to promote the dissemination of colorectal cancer

Down-regulation of GADD45A enhances chemosensitivity in melanoma

Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms

An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)

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