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Nature Communications (2)
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Showing 1–7 of 7 results

Advanced filters: Author: Linda C. Meiser Clear advanced filters

DNA synthesis for true random number generation

Large volumes of true random numbers are needed for increasing requirements of secure data encryption. Here the authors use the stochastic nature of DNA synthesis to obtain millions of gigabytes of unbiased randomness.

Linda C. Meiser
Julian Koch
Robert N. Grass
ResearchOpen Access18 Nov 2020
Nature Communications

Volume: 11, P: 1-9
Reading and writing digital data in DNA

DNA has the capacity to store large amounts of information for very long durations. This protocol describes encoding of digital files as DNA and the error-free retrieval of the stored data from the sequenced data.

Linda C. Meiser
Philipp L. Antkowiak
Robert N. Grass
Protocols29 Nov 2019
Nature Protocols

Volume: 15, P: 86-101
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Helleday and colleagues describe a nanomolar MTHFD2 inhibitor that causes replication stress and DNA damage accumulation in cancer cells via thymidine depletion, demonstrating a potential therapeutic strategy in AML tumors in vivo.

Nadilly Bonagas
Nina M. S. Gustafsson
Thomas Helleday
ResearchOpen Access28 Feb 2022
Nature Cancer

Volume: 3, P: 156-172
Synthetic DNA applications in information technology

Synthetic DNA is the basis for promising technologies in data storage, barcoding, computing 62 and sercurity. In this review, the authors provide an overview of the field and its future.

Linda C. Meiser
Bichlien H. Nguyen
Robert N. Grass
ReviewsOpen Access17 Jan 2022
Nature Communications

Volume: 13, P: 1-13
Information decay and enzymatic information recovery for DNA data storage

An enzymatic repair system is described which repairs nicked DNA in DNA libraries, and simulations of damage and repair suggests this enzymatic repair step is beneficial for DNA data storage.

Linda C. Meiser
Andreas L. Gimpel
Robert N. Grass
ResearchOpen Access20 Oct 2022
Communications Biology

Volume: 5, P: 1-9
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14
Streamlined genetic education is effective in preparing women newly diagnosed with breast cancer for decision making about treatment-focused genetic testing: a randomized controlled noninferiority trial

Veronica F. Quinn
Bettina Meiser
Gillian Mitchell
Research29 Sept 2016
Genetics in Medicine

Volume: 19, P: 448-456