The role of cellular stress responses in ovarian aging remains incompletely understood. In this study, the authors identify NCOA7 as a facilitator of autophagic clearance of stress granules in granulosa cells, conveying protection against ovarian aging. Loss of NCOA7 promotes ovarian aging, whereas its expression via mRNA delivery delays aging.
- Ting Dong
- Nianyu Li
- Xue Jiao