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Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages

Here the authors isolate monoclonal antibodies specific for Plasmodium vivax apical membrane antigen 1, and characterize the epitope of one antibody that inhibits invasion of reticulocytes and hepatocytes, and reduces liver infection in a mouse model.

Anna C. Winnicki
Melanie H. Dietrich
Christopher L. King
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-16
YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates

Inés Bouzón-Arnáiz
Mukul Rawat
Xavier Fernàndez-Busquets
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-12

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Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages

YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates

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