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Body mass index and benign prostatic hyperplasia correlate with urinary microbiome diversity and lower urinary tract symptoms in men

Bowie et al. investigate the urinary microbiome in a large cohort of community dwelling men age 65 and older from the Osteoporotic Fractures in Men Study (MrOS) study. They identify several associations with the diversity of the urinary microbiome and benign prostatic hyperplasia, age, and body mass index.

Kate R. Bowie
Mark Garzotto
Lisa Karstens
ResearchOpen Access07 May 2025
Communications Medicine

Volume: 5, P: 1-9
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
Cohort-based learning for microbiome research community standards

Julia M. Kelliher
Marisa Rudolph
Emiley A. Eloe-Fadrosh
Correspondence17 Apr 2023
Nature Microbiology

Volume: 8, P: 751-753
A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis

Yukiko K. Nakamura
Christina Metea
Phoebe Lin
ResearchOpen Access04 Jul 2023
Scientific Reports

Volume: 13, P: 1-14
Short chain fatty acids ameliorate immune-mediated uveitis partially by altering migration of lymphocytes from the intestine

Yukiko K. Nakamura
Cathleen Janowitz
Phoebe Lin
ResearchOpen Access18 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
Community profiling of the urinary microbiota: considerations for low-biomass samples

The low biomass of the urinary microbiota presents methodological challenges for studying their role in urological diseases. Here, the authors describe methods for urinary microbiota profiling, and discuss important technical considerations for sampling, DNA sequencing, data processing and downstream analysis.

Lisa Karstens
Mark Asquith
Shannon K. McWeeney
Reviews12 Oct 2018
Nature Reviews Urology

Volume: 15, P: 735-749
Reporting guidelines for human microbiome research: the STORMS checklist

The STORMS tool provides guidance for concise and complete reporting of microbiome studies to facilitate manuscript preparation, peer review, reader comprehension of publications, and comparative analysis of published results.

Chloe Mirzayi
Audrey Renson
Levi Waldron
Reviews17 Nov 2021
Nature Medicine

Volume: 27, P: 1885-1892
Benchmarking DNA isolation kits used in analyses of the urinary microbiome

Lisa Karstens
Nazema Y. Siddiqui
Tatyana A. Sysoeva
ResearchOpen Access17 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14

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Body mass index and benign prostatic hyperplasia correlate with urinary microbiome diversity and lower urinary tract symptoms in men

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Cohort-based learning for microbiome research community standards

A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis

Short chain fatty acids ameliorate immune-mediated uveitis partially by altering migration of lymphocytes from the intestine

Community profiling of the urinary microbiota: considerations for low-biomass samples

Reporting guidelines for human microbiome research: the STORMS checklist

Benchmarking DNA isolation kits used in analyses of the urinary microbiome

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

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