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Scientific Reports (2)
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Showing 1–4 of 4 results

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Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model

Renner et al. evaluate the impacts of different types of glycan moieties on the immunogenicity of SARS-CoV-2 spike in a mouse model. The presence of complex type glycans correlate with increased levels of neutralizing antibodies.

Tyler M. Renner
Matthew Stuible
Yves Durocher
ResearchOpen Access11 Apr 2025
Communications Medicine

Volume: 5, P: 1-12
Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters

Felicity C. Stark
Bassel Akache
Martin Handfield
ResearchOpen Access13 Jun 2022
Scientific Reports

Volume: 12, P: 1-11
Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

Bassel Akache
Tyler M. Renner
Michael J. McCluskie
ResearchOpen Access08 Nov 2021
Scientific Reports

Volume: 11, P: 1-17
Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern

Bassel Akache
Tyler M. Renner
Michael J. McCluskie
ResearchOpen Access12 Oct 2022
npj Vaccines

Volume: 7, P: 1-7