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Cell Death & Disease (1)
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Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis

Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.

Marie Bobowski-Gerard
Clémence Boulet
Jérôme Eeckhoute
ResearchOpen Access10 Sept 2022
Nature Communications

Volume: 13, P: 1-20
O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

Ninon Very
Clémence Boulet
Jérôme Eeckhoute
ResearchOpen Access03 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-22

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Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis

O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

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