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Advanced filters: Author: Loïck Lancien Clear advanced filters

  • BSEP (ABCB11) is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. Here, authors report cryo-EM structures of BSEP providing structural and functional insight into the mechanism of bile salt extrusion and small-molecule inhibition.

    • Hongtao Liu
    • Rossitza N. Irobalieva
    • Kaspar P. Locher
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12