The cell of origin for high-grade serous carcinoma (HGSC) remains to be determined. Here, the authors characterize the different cell types and states of the mouse uterine tube and identify transitional pre-ciliated cells as a cancer-prone cell state, which could be targeted therapeutically.
- Andrea Flesken-Nikitin
- Coulter Q. Ralston
- Alexander Yu. Nikitin
