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Advanced filters: Author: Lorena Zubovic Clear advanced filters

  • Rational design of the RNA recognition motif (RRM) of Rbfox promotes sequence-specific interaction with the terminal loop of miR-21 precursor. Replacement of the Dicer PAZ domain with this engineered Rbfox RRM enables specific degradation of pre-miR-21.

    • Yu Chen
    • Fan Yang
    • Gabriele Varani
    Research
    Nature Chemical Biology
    Volume: 12, P: 717-723