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Advanced filters: Author: Lorenz Eing Clear advanced filters

  • A bifunctional AURORA-A degrader induces the fast and specific degradation of this kinase in cancer cell lines, which enables targeting of non-catalytic, oncogenic functions of AURORA-A resulting in S-phase arrest and rampant apoptosis.

    • Bikash Adhikari
    • Jelena Bozilovic
    • Elmar Wolf
    Research
    Nature Chemical Biology
    Volume: 16, P: 1179-1188