LL37 is an antimicrobial peptide that is overexpressed in skin lesions from psoriasis patients and activates innate immunity. Here the authors show that CD4 and CD8 T cells specific for LL37 are present in the circulation of patients with psoriasis, produce inflammatory cytokines and correlate with disease activity.
- Roberto Lande
- Elisabetta Botti
- Loredana Frasca
