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Advanced filters: Author: Lukas Ramsauer Clear advanced filters
  • Tumour-derived prostaglandin E2, signaling through its receptors EP2 and EP4, is shown to restrain the responses of tumour-infiltrating stem-like TCF1+CD8+ T lymphocytes, and modulation of T cell EP2 and EP4 can restore anticancer immunity.

    • Sebastian B. Lacher
    • Janina Dörr
    • Jan P. Böttcher
    ResearchOpen Access
    Nature
    Volume: 629, P: 417-425