Vitamin D insufficiency is associated with the severity of oxidative stress in vitiligo patients. This study provides new insights into the mechanism of vitamin D as a treatment for vitiligo; it protects melanocytes against oxidative stress by activating Wnt/β-catenin signaling. Targeting this signaling could be a useful approach to improve treatment for vitiligo.
- Luyan Tang
- Wei Fang
- Jinhua Xu