Nature Search

Role of biogenic silica in the removal of iron from the Antarctic seas

Iron plays a key role in controlling biological production in the Southern Ocean, yet mechanisms regulating iron availability are not completely understood. Here, Ingall et al.show that structural incorporation of reduced, organic iron into biogenic silica represents a new and substantial removal pathway.

Ellery D. Ingall
Julia M. Diaz
Jay A. Brandes
Research10 Jun 2013
Nature Communications

Volume: 4, P: 1-6
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus infection, which is restored by exogenous IFNβ.

Aran Singanayagam
Nicholas Glanville
Sebastian L. Johnston
ResearchOpen Access08 Jun 2018
Nature Communications

Volume: 9, P: 1-16
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
The ‘Tully monster’ is a vertebrate

The Tully monster (Tullimonstrum), a problematic fossil from the 309–307-million-year-old Mazon Creek biota of Illinois, is shown to be not only a vertebrate but also akin to lampreys, increasing the morphological disparity of that group.

Victoria E. McCoy
Erin E. Saupe
Derek E. G. Briggs
Research16 Mar 2016
Nature

Volume: 532, P: 496-499
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Endothelial Antioxidant-1: a Key Mediator of Copper-dependent Wound Healing in vivo

Archita Das
Varadarajan Sudhahar
Tohru Fukai
ResearchOpen Access26 Sept 2016
Scientific Reports

Volume: 6, P: 1-16
Synchrotron-based X-ray fluorescence microscopy enables multiscale spatial visualization of ions involved in fungal lignocellulose deconstruction

Grant Kirker
Sam Zelinka
Joseph E. Jakes
ResearchOpen Access31 Jan 2017
Scientific Reports

Volume: 7, P: 1-15

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Role of biogenic silica in the removal of iron from the Antarctic seas

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

Mapping the human genetic architecture of COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

A second update on mapping the human genetic architecture of COVID-19

The ‘Tully monster’ is a vertebrate

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Endothelial Antioxidant-1: a Key Mediator of Copper-dependent Wound Healing in vivo

Synchrotron-based X-ray fluorescence microscopy enables multiscale spatial visualization of ions involved in fungal lignocellulose deconstruction

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