The tumour immune microenvironment is known to be suppressive to immune cells, but the causal functional and metabolic cues are not fully known. Here authors show that tumour cells skew the metabolism of multiple types of intra-tumour dendritic cells via their own altered carbohydrate pattern, which could be mitigated by the inhibition of lactate transport.
- Camille Niveau
- Mélanie Cettour-Cave
- Caroline Aspord
