Nature Search

Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A^b

Lymphocyte activation gene-3 (LAG3) is an immune checkpoint protein recently approved as a target for anti-melanoma therapy. Here, the authors solve the structure of mouse LAG3 bound to MHC-II to show that LAG3 blocks MHC-II/CD4 interactions, thereby implicating a potential mechanism of LAG3-mediated immune suppression.

Qianqian Ming
Daniel Antfolk
Vincent C. Luca
ResearchOpen Access29 Aug 2024
Nature Communications

Volume: 15, P: 1-11
Predicted and observed coronal structure

M. WALDMEIER
Research17 Feb 1977
Nature

Volume: 265, P: 611
Maternal nutrition and the sex ratio at birth

J. P. W. RIVERS
M. A. CRAWFORD
Research22 Nov 1974
Nature

Volume: 252, P: 297-298
Hydromagnetic dynamo in the cores of Uranus and Neptune

M. Torbett
R. Smoluchowski
Research17 Jul 1980
Nature

Volume: 286, P: 237-239
Structure of the membrane-pore-forming fragment of colicin A

M. W. Parker
F. Pattus
D. Tsernoglou
Research05 Jan 1989
Nature

Volume: 337, P: 93-96
Fractionation of Nuclear Weapon Debris

C. SHARP COOK
R. L. MATHER
F. M. TOMNOVEC
Research24 Sept 1960
Nature

Volume: 187, P: 1100-1101
Structure of influenza haemagglutinin at the pH of membrane fusion

Per A. Bullough
Frederick M. Hughson
Don C. Wiley
Research01 Sept 1994
Nature

Volume: 371, P: 37-43
A two-dimensional type I superionic conductor

Superionic conductors present liquid-like ionic diffusivity with applications ranging from energy storage to thermoelectrics. A two-dimensional type I superionic conductor α-KAg₃Se₂ is now reported and should help to design other materials with tailored ionic conductivities and phase transitions.

Alexander J. E. Rettie
Jingxuan Ding
Mercouri G. Kanatzidis
Research22 Jul 2021
Nature Materials

Volume: 20, P: 1683-1688
Velocity of Negative Ions in Hydrogen at Atmospheric Pressure

A. M. TYNDALL
Research01 Oct 1910
Nature

Volume: 84, P: 530-531
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Long distance spin communication in chemical vapour deposited graphene

Although graphene promises long spin coherence lengths in spintronic devices, state-of-the-art performance has been limited to exfoliated flakes, limiting industrial scalability. Here, Kumalakar et al. demonstrate long-distance spin transport in large-scale chemical vapour-deposited graphene.

M. Venkata Kamalakar
Christiaan Groenveld
Saroj P. Dash
Research10 Apr 2015
Nature Communications

Volume: 6, P: 1-8
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association analyses of 41,917 bipolar disorder cases and 371,549 controls of European ancestry provide new insights into the etiology of this disorder and identify novel therapeutic leads and potential opportunities for drug repurposing.

Niamh Mullins
Andreas J. Forstner
Ole A. Andreassen
Research17 May 2021
Nature Genetics

Volume: 53, P: 817-829
Apparent competition drives community-wide parasitism rates and changes in host abundance across ecosystem boundaries

Species sharing a common enemy such as a parasitoid or predator can indirectly affect one another. Here, Frost et al. use quantitative food-web data from communities of caterpillar hosts to show experimentally that apparent competition is important in predicting food-web structure across habitats.

Carol M. Frost
Guadalupe Peralta
Jason M. Tylianakis
ResearchOpen Access31 Aug 2016
Nature Communications

Volume: 7, P: 1-12
Chloroplast DNA sequence from a Miocene Magnolia species

Edward M. Golenberg
David E. Giannasi
Gerard Zurawski
Research12 Apr 1990
Nature

Volume: 344, P: 656-658
Cytolytically active murine T-cell hybrids

M. Nabholz
M. Cianfriglia
J. P. Johnson
Research02 Oct 1980
Nature

Volume: 287, P: 437-440
LFA-1 but not Lyt-2 is associated with killing activity of cytotoxic T lymphocyte hybridomas

Y. Kaufmann
P. Golstein
Z. Eshhar
Research25 Nov 1982
Nature

Volume: 300, P: 357-360
Direct observation of a transverse periodicity in collagen fibrils

John M. Squire
Alan Freundlich
Research27 Nov 1980
Nature

Volume: 288, P: 410-413
Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
Amendments and Corrections11 Dec 2013
Nature

Volume: 505, P: 248
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

An inhibitor of NAPE-PLD involved in lipid biosynthesis lowers levels of the endocannabinoid anandamide and other N-acylethanolamines in cells and mouse brain and activates the hypothalamus–pituitary–adrenal axis and impaired fear extinction.

Elliot D. Mock
Mohammed Mustafa
Mario van der Stelt
Research11 May 2020
Nature Chemical Biology

Volume: 16, P: 667-675
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
Production of an H–2-related suppressor factor by a hybrid T-cell line

M. J. TAUSSIG
J. R. F. CORVALÁN
A. HOLLIMAN
Research25 Jan 1979
Nature

Volume: 277, P: 305-308
Light in the dark

Elliot M. Meyerowitz
News & Views03 Dec 1992
Nature

Volume: 360, P: 419
Autologous T cell therapy for MAGE-A4⁺ solid cancers in HLA-A*02⁺ patients: a phase 1 trial

In a phase 1 dose-escalation trial in patients with nine different types of solid tumors, MAGE-A4-specific T cells had an acceptable safety profile and exhibited an encouraging overall response rate in patients with synovial sarcoma.

David S. Hong
Brian A. Van Tine
Marcus O. Butler
ResearchOpen Access09 Jan 2023
Nature Medicine

Volume: 29, P: 104-114
The association of an HPV16 oncogene variant with HLA-B7 has implications for vaccine design in cervical cancer

J.R.M. Ellis
P.J. Keating
P.L. Stern
Research01 May 1995
Nature Medicine

Volume: 1, P: 464-470
Species Specificity in Growth Regulatory Effects of Cellular Interaction

HARRY EAGLE
ELLIOT M. LEVINE
HILARY KOPROWSKI
Research19 Oct 1968
Nature

Volume: 220, P: 266-269
Formation of Mammato-Cloud

C. K. M. DOUGLAS
Research29 Mar 1924
Nature

Volume: 113, P: 462
Abnormal developments

Elliot M. Meyerowitz
News & Views03 Oct 1991
Nature

Volume: 353, P: 385-386
Cadmium and cobalt substitution for zinc in a marine diatom

N. M. Price
F. M. M. Morel
Research12 Apr 1990
Nature

Volume: 344, P: 658-660
Early Proterozoic climates and plate motions inferred from major element chemistry of lutites

H. W. Nesbitt
G. M. Young
Research21 Oct 1982
Nature

Volume: 299, P: 715-717
SMN oligomerization defect correlates with spinal muscular atrophy severity

Christian L. Lorson
John Strasswimmer
Elliot J. Androphy
Research01 May 1998
Nature Genetics

Volume: 19, P: 63-66
An innovative cellular medicine approach via the utilization of novel nanotechnology-based biomechatronic platforms as a label-free biomarker for early melanoma diagnosis

Jassim A. Alqabandi
Rhiannon David
Kamal Youcef-Toumi
ResearchOpen Access03 Dec 2024
Scientific Reports

Volume: 14, P: 1-63
Macroscopic waves, biological clocks and morphogenesis driven by light in a giant unicellular green alga

Self-organised waves propagate throughout the alga Caulerpa. Light temporal patterns control the waves and algal morphology, potentially tying light-synchronized self-oscillations to one of the mysteries of single-cell development, morphogenesis.

Eldad Afik
Toni J. B. Liu
Elliot M. Meyerowitz
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-8
Long-range charge carrier mobility in metal halide perovskite thin-films and single crystals via transient photo-conductivity

Charge carrier mobility is a fundamental property of semiconductors. The authors of this study demonstrate a novel way to estimate long-range mobilities of perovskite thin-films and single crystals by taking early-time carrier dynamics into account.

Jongchul Lim
Manuel Kober-Czerny
Henry J. Snaith
ResearchOpen Access20 Jul 2022
Nature Communications

Volume: 13, P: 1-9
Induction of an IgM anti-(bovine)-IgG response in mice by bacterial lipopolysaccharide

D. W. DRESSER
A. M. POPHAM
Research01 Dec 1976
Nature

Volume: 264, P: 552-554
Two variant surface glycoproteins of Trypanosoma Brucei of different sequence classes have similar 6 Å resolution X-ray structures

P. Metcalf
M. Blum
D. C. Wiley
Research01 Jan 1987
Nature

Volume: 325, P: 84-86
Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior

Neural circuitry mechanism which invigorates an animal to go from basal breathing which serves the purpose of gas exchange, to engage in the voluntary act of sniffing is not fully understood. These results from Johnson and colleagues support a model whereby sniffing can be initiated by dopamine’s actions upon ventral striatum neurons.

Natalie L. Johnson
Anamaria Cotelo-Larrea
Daniel W. Wesson
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-23
Spectroscopic observation of a catalyst surface in a reactive atmosphere at high pressure

Geoffrey D. Moggridge
Trevor Rayment
Richard M. Lambert
Research20 Aug 1992
Nature

Volume: 358, P: 658-660
Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis

Joint analysis of 11 major psychiatric disorders identifies four broad factor underlying genetic correlations among the disorders. Association analyses detect 152 loci acting on these factors and identify 9 loci that act heterogeneously across disorders.

Andrew D. Grotzinger
Travis T. Mallard
Michel G. Nivard
Research05 May 2022
Nature Genetics

Volume: 54, P: 548-559
Layer specific observation of slow thermal equilibration in ultrathin metallic nanostructures by femtosecond X-ray diffraction

Heat transport in ultrathin metal layers is important for potential applications in optical‐magnetic switching, but difficult to access experimentally. Here, the authors use ultrafast X‐ray diffraction to directly probe and explain unexpected time‐dependent transport behavior in Au–Ni nanolayers.

J. Pudell
A. A. Maznev
M. Bargheer
ResearchOpen Access20 Aug 2018
Nature Communications

Volume: 9, P: 1-7
Mechanisms of sputtering

M. W. THOMPSON
Research25 Jan 1979
Nature

Volume: 277, P: 326-327
Rapid evolution of a Gulf Stream warm-core ring

Terrence Joyce
Richard Backus
Peter Wiebe
Research26 Apr 1984
Nature

Volume: 308, P: 837-840
Shared heritability of human face and brain shape

A multivariate genome-wide association study highlighting loci that influence both face and brain shape suggesting shared developmental axes during early embryogenesis. These loci did not overlap with those governing behavioral–cognitive traits or neuropsychiatric risk indicating divergence between early brain development and cognitive function.

Sahin Naqvi
Yoeri Sleyp
Peter Claes
Research05 Apr 2021
Nature Genetics

Volume: 53, P: 830-839
A phenylethylamine oxidising defect in migraine

M. SANDLER
M. B. H. YOUDIM
EDDA HANINGTON
Research26 Jul 1974
Nature

Volume: 250, P: 335-337
A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells

Shahid M. Ali
Michael J. Geisow
Robert D. Burgoyne
Research27 Jul 1989
Nature

Volume: 340, P: 313-315
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis

Down syndrome has a high co-morbidity with immune and hematopoietic disorders. Here, the authors perform an epigenome-wide association study in newborns with and without Down syndrome to find differential methylation across the genome, including in hematopoietic regulators RUNX1 and FLI1.

Ivo S. Muskens
Shaobo Li
Adam J. de Smith
ResearchOpen Access05 Feb 2021
Nature Communications

Volume: 12, P: 1-15
A Middle Miocene hominoid from Thailand and orangutan origins

Yaowalak Chaimanee
Dominique Jolly
Jean-Jacques Jaeger
Research06 Mar 2003
Nature

Volume: 422, P: 61-65
Mapping genotypes to chromatin accessibility profiles in single cells

The JAK2^V617F mutation leads to epigenetic rewiring in a cell-intrinsic and cell-type-specific manner, influencing inflammation states and differentiation trajectories in patients with myeloproliferative neoplasms.

Franco Izzo
Robert M. Myers
Dan A. Landau
Research08 May 2024
Nature

Volume: 629, P: 1149-1157
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

An orally bioavailable small-molecule active-site inhibitor of the phosphatases PTPN2 and PTPN1, ABBV-CLS-484, demonstrates immunotherapeutic efficacy in mouse models of cancer resistant to PD-1 blockade.

Christina K. Baumgartner
Hakimeh Ebrahimi-Nik
Robert T. Manguso
ResearchOpen Access04 Oct 2023
Nature

Volume: 622, P: 850-862
Processing of tumour necrosis factor-α precursor by metalloproteinases

A. J. H. Gearing
P. Beckett
K. Woolley
Research18 Aug 1994
Nature

Volume: 370, P: 555-557
Metal mediated sterol receptor-DNA complex association and dissociation determined by electrospray ionization mass spectrometry

Timothy D. Veenstra
Linda M. Benson
Stephen Naylor
Research01 Mar 1998
Nature Biotechnology

Volume: 16, P: 262-266

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