Nature Search

Proof-of-concept study evaluating humoral primary immunodeficiencies via CJ:KREC ratio and serum BAFF level

Elisa Ochfeld
Amer Khojah
Lauren M. Pachman
ResearchOpen Access21 Jun 2024
Scientific Reports

Volume: 14, P: 1-7
Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

The mechanisms by which measles virus infection induces transient immune suppression in humans are poorly understood. Here, Laksono and colleagues characterise the pathogenesis of measles-associated immune suppression in unvaccinated children, and shed new light on the long-term effects of measles on the host.

Brigitta M. Laksono
Rory D. de Vries
Rik L. de Swart
ResearchOpen Access23 Nov 2018
Nature Communications

Volume: 9, P: 1-10
The potential of emerging bio-based products to reduce environmental impacts

Zuiderveen and colleagues find that emerging bio-based products have on average 45% lower greenhouse gas life cycle emissions compared to their fossil counterparts, yet, there is a large variation between individual bio-based products with none of them reaching netzero emissions.

Emma A. R. Zuiderveen
Koen J. J. Kuipers
Mark A. J. Huijbregts
ResearchOpen Access21 Dec 2023
Nature Communications

Volume: 14, P: 1-7
Greenhouse-gas payback times for crop-based biofuels

Greenhouse-gas payback times are derived for biofuel production systems using five feedstocks under high- and low-input farm management to assess replacement of natural vegetation with crop-based biofuels. Estimates ranged from 1–162 years.

P. M. F. Elshout
R. van Zelm
M. A. J. Huijbregts
Research11 May 2015
Nature Climate Change

Volume: 5, P: 604-610
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia

Activating mutations in Interleukin-7 receptor alpha (IL7Ra) have been reported in B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) but its role in leukaemogenesis is not clear. Here, the authors show that activation of IL7Ra in primary human hematopoietic progenitors initiates preleukaemia and cooperates with CDKN2A silencing to develop BCP-ALL.

Ifat Geron
Angela Maria Savino
Shai Izraeli
ResearchOpen Access03 Feb 2022
Nature Communications

Volume: 13, P: 1-12
Molecular defects in T- and B-cell primary immunodeficiency diseases

Charlotte Cunningham-Rundles
Prashant P. Ponda
Reviews01 Nov 2005
Nature Reviews Immunology

Volume: 5, P: 880-892
B-cell maturation and antibody responses in individuals carrying a mutated CD19 allele

H Artac
I Reisli
M C van Zelm
Research06 May 2010
Genes & Immunity

Volume: 11, P: 523-530
Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin

Magdalena B. Rother
Kristin Jensen
Menno C. van Zelm
ResearchOpen Access23 Sept 2016
Scientific Reports

Volume: 6, P: 1-13
Differential effects of Cytomegalovirus carriage on the immune phenotype of middle-aged males and females

Marieke van der Heiden
Menno C. van Zelm
Anne-Marie Buisman
ResearchOpen Access31 May 2016
Scientific Reports

Volume: 6, P: 1-12
High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression

R P Kuiper
E F P M Schoenmakers
P M Hoogerbrugge
Research19 Apr 2007
Leukemia

Volume: 21, P: 1258-1266
T-, B- and NK-lymphoid, but not myeloid cells arise from human CD34⁺CD38⁻CD7⁺ common lymphoid progenitors expressing lymphoid-specific genes

I Hoebeke
M De Smedt
G Leclercq
Research14 Dec 2006
Leukemia

Volume: 21, P: 311-319
Salinity stress tolerance and omics approaches: revisiting the progress and achievements in major cereal crops

Pardeep Kumar
Mukesh Choudhary
Kadambot H. M. Siddique
Reviews05 Mar 2022
Heredity

Volume: 128, P: 497-518
Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

B Paiva
N-C Gutiérrez
J-F San Miguel
Research15 Feb 2012
Leukemia

Volume: 26, P: 1862-1869
Novel mutations in a Japanese patient with CD19 deficiency

H Kanegane
K Agematsu
T Miyawaki
Research20 Sept 2007
Genes & Immunity

Volume: 8, P: 663-670
Artemis splice defects cause atypical SCID and can be restored in vitro by an antisense oligonucleotide

H IJspeert
A C Lankester
M van der Burg
Research10 Mar 2011
Genes & Immunity

Volume: 12, P: 434-444
Basal Ca²⁺ signaling is particularly increased in mutated chronic lymphocytic leukemia

A F Muggen
S Y Pillai
A W Langerak
Research11 Jun 2014
Leukemia

Volume: 29, P: 321-328
Persistent polyclonal B-cell lymphocytosis: extensively proliferated CD27+IgM+IgD+ memory B cells with a distinctive immunophenotype

M A Berkowska
C Grosserichter-Wagener
M C van Zelm
Correspondence19 Feb 2014
Leukemia

Volume: 28, P: 1560-1564
Differentiation stage of myeloma plasma cells: biological and clinical significance

B Paiva
N Puig
J F San-Miguel
Research01 Aug 2016
Leukemia

Volume: 31, P: 382-392
Genetic and epigenetic determinants mediate proneness of oncogene breakpoint sites for involvement in TCR translocations

N S D Larmonie
A van der Spek
A W Langerak
Research05 Dec 2013
Genes & Immunity

Volume: 15, P: 72-81

Search

Proof-of-concept study evaluating humoral primary immunodeficiencies via CJ:KREC ratio and serum BAFF level

Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

The potential of emerging bio-based products to reduce environmental impacts

Greenhouse-gas payback times for crop-based biofuels

An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia

Molecular defects in T- and B-cell primary immunodeficiency diseases

B-cell maturation and antibody responses in individuals carrying a mutated CD19 allele

Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin

Differential effects of Cytomegalovirus carriage on the immune phenotype of middle-aged males and females

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression

T-, B- and NK-lymphoid, but not myeloid cells arise from human CD34⁺CD38⁻CD7⁺ common lymphoid progenitors expressing lymphoid-specific genes

Salinity stress tolerance and omics approaches: revisiting the progress and achievements in major cereal crops

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

Novel mutations in a Japanese patient with CD19 deficiency

Artemis splice defects cause atypical SCID and can be restored in vitro by an antisense oligonucleotide

Basal Ca²⁺ signaling is particularly increased in mutated chronic lymphocytic leukemia

Persistent polyclonal B-cell lymphocytosis: extensively proliferated CD27+IgM+IgD+ memory B cells with a distinctive immunophenotype

Differentiation stage of myeloma plasma cells: biological and clinical significance

Genetic and epigenetic determinants mediate proneness of oncogene breakpoint sites for involvement in TCR translocations

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