Nature Search

Polarity of the CRISPR roadblock to transcription

Hall et al. discovered the molecular mechanism for the polarity of the CRISPR roadblock to transcription: RNA polymerase progression can collapse the R-loop formed by a bound dCas to allow read-through from the PAM-distal side. Guide RNA modifications allow modulation of the dCas R-loop stability.

Porter M. Hall
James T. Inman
Michelle D. Wang
ResearchOpen Access05 Dec 2022
Nature Structural & Molecular Biology

Volume: 29, P: 1217-1227
Gene Replication, Ultra-Violet Sensitivity and the Cell Cycle

M. M. SWANN
Research31 Mar 1962
Nature

Volume: 193, P: 1222-1227
Attosecond clocking of correlations between Bloch electrons

By forcing electron–hole pairs onto closed trajectories attosecond clocking of delocalized Bloch electrons is achieved, enabling greater understanding of unexpected phase transitions and quantum-dynamic phenomena.

J. Freudenstein
M. Borsch
R. Huber
Research12 Oct 2022
Nature

Volume: 610, P: 290-295
The wide-binary origin of (2014) MU₆₉-like Kuiper belt contact binaries

The high obliquity and low rotation period of the Kuiper belt object (2014) MU₆₉ and other similar contact binaries is successfully reproduced from the collision and post-collision characteristics of initially wide binaries.

Evgeni Grishin
Uri Malamud
Christoph M. Schäfer
Research22 Apr 2020
Nature

Volume: 580, P: 463-466
Ion Exchange Theory of Coagulation

M. MIRNIK
Research10 Aug 1963
Nature

Volume: 199, P: 555-558
Visualization of Minute Mechanical-Excitation/Relaxation Wave-front Propagation in Myocardial Tissue

Hiroshi Kanai
Motonao Tanaka
ResearchOpen Access23 Sept 2010
Nature Precedings

P: 1
Product lambda-doublet ratios as an imprint of chemical reaction mechanism

Propensity for a given Λ-doublet level is a common feature in many chemical reactions, but has so far remained unexplained. Here, the authors show how to predict computationally those propensities and relate them to the reaction mechanism on concurrent potential energy surfaces.

P. G. Jambrina
A. Zanchet
F. J. Aoiz
ResearchOpen Access11 Nov 2016
Nature Communications

Volume: 7, P: 1-8
Bennu’s near-Earth lifetime of 1.75 million years inferred from craters on its boulders

Analysis of the size and depth of craters on boulders on the asteroid (101955) Bennu indicates that Bennu has been in near-Earth space for 1.75 ± 0.75 million years.

R.-L. Ballouz
K. J. Walsh
D. S. Lauretta
Research26 Oct 2020
Nature

Volume: 587, P: 205-209
Phosphorylation of Xylose by Extracts of Pseudomonas Hydrophila

ROLF M. HOCHSTER
R. WADE WATSON
Research30 Aug 1952
Nature

Volume: 170, P: 357-358
Decoding drivers of carbon flux attenuation in the oceanic biological pump

In situ experimental findings from six contrasting oceanic regimes, at multiple mesopelagic depths, are used to determine the mechanisms that drive microbially mediated carbon flux attenuation in the oceanic biological pump.

M. Bressac
E. C. Laurenceau-Cornec
P. W. Boyd
ResearchOpen Access11 Sept 2024
Nature

Volume: 633, P: 587-593
Single artificial atoms in silicon emitting at telecom wavelengths

Carbon-related point defects can be isolated in a commercial silicon-on-insulator wafer, acting as artificial atoms that provide efficient polarized single-photon emission at wavelengths suitable for long-distance propagation in optical fibres.

W. Redjem
A. Durand
G. Cassabois
Research23 Nov 2020
Nature Electronics

Volume: 3, P: 738-743
Minimal Model for the Mechanism of Antibody Induction and Paralysis by Antigen

P. A. BRETSCHER
M. COHN
Research02 Nov 1968
Nature

Volume: 220, P: 444-448
Water ice in the debris disk around HD 181327

The James Webb Space Telescope has detected water ice in the cold debris disk (analogous to the Kuiper belt) around the star HD 181327.

Chen Xie
Christine H. Chen
Jarron M. Leisenring
Research14 May 2025
Nature

Volume: 641, P: 608-611
Proton Transfer in Nucleic Acid

Y. KYOGOKU
T. SHIMANOUCHI
I. WATANABE
Research04 Aug 1962
Nature

Volume: 195, P: 460-462
Detections of interstellar aromatic nitriles 2-cyanopyrene and 4-cyanopyrene in TMC-1

Wenzel et al. detect radio signatures of two forms of cyanopyrene, a small molecular sheet of carbon, which can be used as indicators of the abundance of pyrene. Their findings suggest that small polycyclic aromatic hydrocarbons must be formed in or transported to the cold interstellar medium.

Gabi Wenzel
Thomas H. Speak
Brett A. McGuire
ResearchOpen Access05 Nov 2024
Nature Astronomy

Volume: 9, P: 262-270
Open-circuit and short-circuit loss management in wide-gap perovskite p-i-n solar cells

A mismatch between quasi-Fermi level splitting and open-circuit voltage is detrimental to wide bandgap perovskite pin solar cells. Here, through theoretical and experimental approaches, the authors optimize n- and p-type interfaces to achieve open-circuit voltage of 1.29 V and T80 of 3500 h at 85 °C.

Pietro Caprioglio
Joel A. Smith
Henry J. Snaith
ResearchOpen Access20 Feb 2023
Nature Communications

Volume: 14, P: 1-13
Secoisopimaranes from Salvia elegans Vahl leaves as antibacterial agents against Staphylococcus aureus

Gabin Thierry M. Bitchagno
Erin M. Garcia
Monique S. J. Simmonds
ResearchOpen Access08 Oct 2025
Scientific Reports

Volume: 15, P: 1-8
In Vivo Study of Cell Kinetics in Acute Leukæmia

A. M. MAUER
VIRGINIA FISHER
Research09 Feb 1963
Nature

Volume: 197, P: 574-576
Segregation of Lymphocyte Populations through Differential Migration

EUGENE M. LANCE
ROBERT N. TAUB
Research01 Mar 1969
Nature

Volume: 221, P: 841-843
Sex Pili and the Classification of Sex Factors in the Enterobacteriaceae

A. M. LAWN
ELINOR MEYNELL
NAOMI DATTA
Research01 Oct 1967
Nature

Volume: 216, P: 343-346
Formation and Morphology of the ‘Buffy Coat’ and Measurement of Density of Blood and Tumour Cells

M. E. A. POWELL
Research17 Mar 1962
Nature

Volume: 193, P: 1047-1050
Some Reactions in the Iron–Carbon System: Application to the Tempering of Martensite

L. J. E. HOFER
E. M. COHN
Research16 Jun 1951
Nature

Volume: 167, P: 977-978
Long-range versus short-range effects in cold molecular ion-neutral collisions

Studies on reactions between cold molecular ions and neutral atoms provide insights into intermolecular interactions. Here the authors explore the kinetics and dynamics of charge-transfer collisions between the cold N\({}_{2}^{+}\) and O\({}_{2}^{+}\) ions and neutral Rb atoms and discuss the role of long- and short-range effects.

Alexander D. Dörfler
Pascal Eberle
Stefan Willitsch
ResearchOpen Access28 Nov 2019
Nature Communications

Volume: 10, P: 1-10
Rapid spectral variability of a giant flare from a magnetar in NGC 253

Observations of a giant flare associated with the starburst galaxy NGC 253 suggest that the flare is probably associated with relativistic plasma in the magnetic field of a magnetar.

O. J. Roberts
P. Veres
E. Burns
Research13 Jan 2021
Nature

Volume: 589, P: 207-210
Cinematographic Recording of the Velocity of Arterial Blood-Flow

J. M. POTTER
D. A. McDONALD
Research07 Oct 1950
Nature

Volume: 166, P: 596-597
Movement of the Ovum in the Reproductive Tract: A Possible Explanation for the Failure of Non-Surgical Ovum Transfers in the Cow

M. J. K. HARPER
J. P. BENNETT
L. E. A. ROWSON
Research27 May 1961
Nature

Volume: 190, P: 789-790
Resonant plasmonic detection of terahertz radiation in field-effect transistors with the graphene channel and the black-As\(_x\)P\(_{1-x}\) gate layer

V. Ryzhii
C. Tang
M. S. Shur
ResearchOpen Access14 Jun 2023
Scientific Reports

Volume: 13, P: 1-10
Multivariable regression models improve accuracy and sensitive grading of antibiotic resistance mutations in Mycobacterium tuberculosis

Here the authors train multivariate logistic regression models on over 52,000 MTBC isolates to associate binary resistance phenotypes for 15 antitubercular drugs with variants extracted from candidate resistance genes, and generate a regression-based catalogue of resistance-associated mutations that achieves higher sensitivity on average than the gold standard with smaller average decreases in specificity and positive predictive value.

Sanjana G. Kulkarni
Sacha Laurent
Maha R. Farhat
ResearchOpen Access04 Mar 2025
Nature Communications

Volume: 16, P: 1-12
Ultrafast room-temperature valley manipulation in silicon and diamond

Control over electron populations in different conduction band minima in semiconductors can be used to store and process information. Now the ultrafast optical manipulation of such electrons at room temperature has been demonstrated in silicon and diamond.

Adam Gindl
Martin Čmel
Martin Kozák
ResearchOpen Access14 Apr 2025
Nature Physics

Volume: 21, P: 947-952
Is an Ectoproct Possible?

CHARLOTTE P. MANGUM
THOMAS J. M. SCHOPF
Research21 Jan 1967
Nature

Volume: 213, P: 264-266
Comparative analysis of light storage in antirelaxation-coated and buffer-gas-filled alkali vapor cells

M. Đujić
D. Buhin
T. Ban
ResearchOpen Access24 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
Relation of Sub-Acute Combined Degeneration of the Cord to Vitamin B₁₂ Deficiency

J. WILSON
M. J. S. LANGMAN
Research19 Nov 1966
Nature

Volume: 212, P: 787-789
Chromosome Marker Studies on the Development of the Haemopoietic System in the Chick Embryo

M. A. S. MOORE
J. J. T. OWEN
Research04 Dec 1965
Nature

Volume: 208, P: 956
Pancreatic Acinar Cell Regeneration

PATRICK J. FITZGERALD
BERNARD M. CAROL
LAWRENCE ROSENSTOCK
Research01 Nov 1966
Nature

Volume: 212, P: 594-596
Genetic Variation in the Biosynthesis of Corticosteroids in Mus musculus

F. M. BADR
S. G. SPICKETT
Research13 Mar 1965
Nature

Volume: 205, P: 1088-1090
A Rapid Method for Determining Phytase Activity of Soil Micro-organisms

M. P. GREAVES
G. ANDERSON
D. M. WEBLEY
Research21 Dec 1963
Nature

Volume: 200, P: 1231-1232
Collapsars as a major source of r-process elements

A rare type of supernova—triggered by the collapse of a rapidly rotating single star—could have provided more than 80 per cent of the r-process elements in the Universe.

Daniel M. Siegel
Jennifer Barnes
Brian D. Metzger
Research08 May 2019
Nature

Volume: 569, P: 241-244
Saving Old Bones: a non-destructive method for bone collagen prescreening

Matt Sponheimer
Christina M. Ryder
Sahra Talamo
ResearchOpen Access26 Sept 2019
Scientific Reports

Volume: 9, P: 1-7
The Ralstonia solanacearum catalase-peroxidase KatG is crucial to survive environmental stresses and also plays a role in plant infection

Jordi Corral
Mercedes Rocafort
Elena G. Orellano
ResearchOpen Access08 Oct 2025
Scientific Reports

Volume: 15, P: 1-14
Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

The ATLAS experiment at the Large Hadron Collider reports a search for charged-lepton-flavour violation in decays of Z bosons into a τ lepton and an electron or muon of opposite charge.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access01 Jul 2021
Nature Physics

Volume: 17, P: 819-825
Proton Magnetic Resonance and the Helix–Coil Transition

E. M. BRADBURY
C. CRANE-ROBINSON
H. W. E. RATTLE
Research02 Mar 1968
Nature

Volume: 217, P: 812-816
Formation of the Initiation Complex using Muscle Messenger RNAs

STUART M. HEYWOOD
Research21 Feb 1970
Nature

Volume: 225, P: 696-698
Electrophoretic and Immunological Studies on Structural Sub-Units of Human Ceruloplasm

M. D. POULIK
Research02 Jun 1962
Nature

Volume: 194, P: 842-844
Population structure, biogeography and transmissibility of Mycobacterium tuberculosis

Mycobacterium tuberculosis is a clonal pathogen that has co-evolved with humans for millennia. Here, Freschi et al. reevaluate the population structure of M. tuberculosis, providing an in-depth analysis of the ancient Indo-Oceanic Lineage 1 and the modern Central Asian Lineage 3, and expanding our understanding of Lineages 2 and 4.

Luca Freschi
Roger Vargas Jr.
Maha Reda Farhat
ResearchOpen Access20 Oct 2021
Nature Communications

Volume: 12, P: 1-11
Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

Mariann Grossman
Steven E. Raper
James M. Wilson
Research01 Apr 1994
Nature Genetics

Volume: 6, P: 335-341
Globin Synthesis in Thalassaemia: An in vitro Study

D. J. WEATHERALL
J. B. CLEGG
M. A. NAUGHTON
Research11 Dec 1965
Nature

Volume: 208, P: 1061-1065
Absolute frequency metrology of buffer-gas-cooled molecular spectra at 1 kHz accuracy level

High-resolution molecular spectroscopy with cryogenic setups is hampered by the lack of a skilled interrogation tool. Here, the authors demonstrate absolute metrology of cold rovibrational spectra at 1 kHz accuracy level, by coupling a Lamb-dip saturated-absorption cavity ring-down spectrometer to a buffer-gas cooling source.

Roberto Aiello
Valentina Di Sarno
Pasquale Maddaloni
ResearchOpen Access16 Nov 2022
Nature Communications

Volume: 13, P: 1-7
Micro-Aerobic Capabilities in Land Plants: Observations on Survival and Growth of Plants Submerged in Fresh and Saline Waters

S. M. SIEGEL
C. GIUMARRO
O. W. DALY
Research26 Mar 1966
Nature

Volume: 209, P: 1330-1334
Scattering of Underwater Sound in Saanich inlet, British Columbia

B. M. BARY
W. E. BARRACLOUGH
R. HERLINVEAUX
Research07 Apr 1962
Nature

Volume: 194, P: 36-37
Two Different Excitatory Transmitters acting on a Single Molluscan Neurone

H. M. GERSCHENFELD
P. ASCHER
L. TAUC
Research28 Jan 1967
Nature

Volume: 213, P: 358-359

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