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British Journal of Cancer (25)
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Showing 1–50 of 60 results

Advanced filters: Author: M Daugaard Clear advanced filters

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

HACE1 is an E3 ligase that promotes degradation of the GTPase Rac1. Here Daugaard et al. show that HACE1 inhibits the activity of Rac1-dependent NADPH oxidase complexes, which reduces the production of cellular reactive oxygen species and cell cycle progression.

Mads Daugaard
Roberto Nitsch
Poul H. Sorensen
ResearchOpen Access17 Jul 2013
Nature Communications

Volume: 4, P: 1-13
Deeply incised submarine glacial valleys beneath the Greenland ice sheet

The bed topography beneath the Greenland ice sheet controls the flow of ice and its discharge into the ocean. A combination of sparse radar soundings of ice thickness and high-resolution ice motion data suggest that many submarine ice-covered valleys extend significantly deeper below sea level and farther inland than thought.

M. Morlighem
E. Rignot
E. Larour
Research18 May 2014
Nature Geoscience

Volume: 7, P: 418-422
Renal function related to different treatment modalities for malignant germ cell tumours

N Aass
SD Fosså
MW Lindegaard
Research01 Nov 1990
British Journal of Cancer

Volume: 62, P: 842-846
High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer

H Nielsen
G Daugaard
B Bruun
Research01 Oct 1992
British Journal of Cancer

Volume: 66, P: 666-667
Cisplatin neurotoxicity in the treatment of metastatic germ cell tumour: time course and prognosis

M von Schlippe
C J Fowler
S J Harland
ResearchOpen Access11 Sept 2001
British Journal of Cancer

Volume: 85, P: 823-826
A multicentre phase II study of carboplatin and prolonged oral etoposide in the treatment of cancer of unknown primary site (CUPS)

E Warner
R Goel
G Gallant
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 2376-2380
Pressure tuning infrared spectroscopic study of cisplatin-induced structural changes in a phosphatidylserine model membrane

KD Taylor
R Goel
PT Wong
Research01 Dec 1995
British Journal of Cancer

Volume: 72, P: 1400-1405
Pathological predictors of metastatic disease in testicular non-seminomatous germ cell tumors: which tumor-node-metastasis staging system?

Glenda Scandura
Thomas Wagner
Daniel M. Berney
Research15 Dec 2020
Modern Pathology

Volume: 34, P: 834-841
Accelerated BEP: a phase I trial of dose-dense BEP for intermediate and poor prognosis metastatic germ cell tumour

Y Rimmer
J Chester
M V Williams
ResearchOpen Access16 Aug 2011
British Journal of Cancer

Volume: 105, P: 766-772
Combined microfluidic enrichment and staining workflow for single-cell analysis of circulating tumor cells in metastatic prostate cancer patients

Caroline Løppke
Amalie M. Jørgensen
Mette Ø. Agerbæk
ResearchOpen Access30 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Adjustment of creatinine clearance improves accuracy of Calvert's formula for carboplatin dosing

Y Ando
H Minami
K Shimokata
Research01 Oct 1997
British Journal of Cancer

Volume: 76, P: 1067-1071
The International Congress of Anthropological and Ethnological Sciences

M. C. BURKITT
News20 Aug 1938
Nature

Volume: 142, P: 363-364
Diuretic response to cyclophosphamide in rats bearing a matrix metalloproteinase-9-producing tumour

Y Mizushima
K Sassa
M Kobayashi
Research01 Oct 1998
British Journal of Cancer

Volume: 78, P: 1030-1034
Does more than one biopsy of the contralateral testis in men with a germ cell tumor add value?

Christina E Hoei-Hansen
Ewa Rajpert-De Meyts
Niels E Skakkebaek
Comments & Opinion23 Oct 2007
Nature Clinical Practice Urology

Volume: 4, P: 652-653
Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division

Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al. provide evidence of an ECM stiffnessmodulated role of Optineurin (OPTN), which regulates HACE1-dependant Rac1 activity and thus controls integrinmediated mechanotransduction and bacterial invasion.

Serena Petracchini
Daniel Hamaoui
Amel Mettouchi
ResearchOpen Access13 Oct 2022
Nature Communications

Volume: 13, P: 1-22
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

Isolation of circulating tumor cells (CTCs) allows for non-invasive disease monitoring and characterization. Here the authors describe an alternative CTC isolation method based on the ability of the malaria rVAR2 protein to specifically bind oncofetal chondroitin sulfate, which is expressed by all cancer cells

Mette Ø. Agerbæk
Sara R. Bang-Christensen
Ali Salanti
ResearchOpen Access16 Aug 2018
Nature Communications

Volume: 9, P: 1-13
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

Intraventricularly delivered monovalent and trivalent CAR T cells exhibit greater therapeutic efficacy as compared with intravenously delivered CAR T cells in medulloblastoma xenograft mouse models and show potency in ependymoma xenograft mouse models.

Laura K. Donovan
Alberto Delaidelli
Michael D. Taylor
Research27 Apr 2020
Nature Medicine

Volume: 26, P: 720-731
Prognostic relevance of the mitotic count and the amount of viable tumour after neoadjuvant chemotherapy for primary, localised, high-grade soft tissue sarcoma

D Andreou
M Werner
P U Tunn
ResearchOpen Access23 Dec 2014
British Journal of Cancer

Volume: 112, P: 455-460
Recent ice melt above a mantle plume track is accelerating the uplift of Southeast Greenland

Unusually rapid uplift of Southeast Greenland is explained as a viscous response to recent deglaciation occurring above mantle weakened by the Iceland plume, according to 3D modelling with a hot plume track that crosses Greenland’s southeast coast.

Maaike F. M. Weerdesteijn
Clinton P. Conrad
ResearchOpen Access26 Dec 2024
Communications Earth & Environment

Volume: 5, P: 1-15
Bilateral germ-cell tumours: 22-year experience at the Institut Gustave Roussy

Ch Theodore
M J Terrier-Lacombe
P Wibault
ResearchOpen Access06 Jan 2004
British Journal of Cancer

Volume: 90, P: 55-59
Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours

JHM Schellens
J Ma
J Verweij
Research01 Jun 1996
British Journal of Cancer

Volume: 73, P: 1569-1575
Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

Laura K. Donovan
Alberto Delaidelli
Michael D. Taylor
Amendments and Corrections27 May 2021
Nature Medicine

Volume: 27, P: 1117-1120
Author Correction: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

Mette Ø. Agerbæk
Sara R. Bang-Christensen
Ali Salanti
Amendments and CorrectionsOpen Access07 Jun 2022
Nature Communications

Volume: 13, P: 1-4
Changes in hemodynamics, renal blood flow and urine output during continuous renal replacement therapies

S. N. Fernández
M. J. Santiago
J. López-Herce
ResearchOpen Access27 Nov 2020
Scientific Reports

Volume: 10, P: 1-11
Application of positron emission tomography imaging to cancer screening

S Yasuda
M Ide
A Shohtsu
ResearchOpen Access05 Dec 2000
British Journal of Cancer

Volume: 83, P: 1607-1611
'VEEP' in children with Hodgkin's disease – a regimen to decrease late sequelae

MER O'Brien
CR Pinkerton
TJ McElwain
Research01 May 1992
British Journal of Cancer

Volume: 65, P: 756-760
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus

M Stanulla
J Wang
PD Aplan
Research01 Apr 1997
Leukemia

Volume: 11, P: 490-496
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death

M Høyer-Hansen
L Bastholm
M Jäättelä
Research20 May 2005
Cell Death & Differentiation

Volume: 12, P: 1297-1309
Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions

S Andersson
M Alemi
E Wilander
ResearchOpen Access04 Jul 2000
British Journal of Cancer

Volume: 83, P: 307-310
Failure-specific prognostic factors after continuous hyperfractionated accelerated radiotherapy (CHART) or conventional radiotherapy in locally advanced non-small-cell lung cancer: A competing risks analysis

Ö U Ataman
S M Bentzen
S Dische
ResearchOpen Access16 Oct 2001
British Journal of Cancer

Volume: 85, P: 1113-1118
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

Judith Bovée and colleagues report the identification of somatic mosaic mutations in IDH1 and IDH2 in tumors from individuals with Ollier disease and Maffucci syndrome, which are non-hereditary skeletal disorders characterized by multiple enchondromas.

Twinkal C Pansuriya
Ronald van Eijk
Judith V M G Bovée
Research06 Nov 2011
Nature Genetics

Volume: 43, P: 1256-1261
High-dose epirubicin is not an alternative to standard-dose doxorubicin in the treatment of advanced soft tissue sarcomas. A study of the EORTC soft tissue and bone sarcoma group

OS Nielsen
P Dombernowsky
T Tursz
Research01 Dec 1998
British Journal of Cancer

Volume: 78, P: 1634-1639
The effect of hypoxia and hyperoxia on nucleoside triphosphate/inorganic phosphate, pO2 and radiation response in an experimental tumour model

M Nordsmark
RJ Maxwell
J Overgaard
Research01 Dec 1997
British Journal of Cancer

Volume: 76, P: 1432-1439
Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction

N Cetinbas
M Daugaard
P H Sorensen
Research06 Oct 2014
Oncogene

Volume: 34, P: 4005-4010
Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

D Walerych
M B Olszewski
A Zylicz
Research14 Sept 2009
Oncogene

Volume: 28, P: 4284-4294
The BAG-1 cochaperone is a negative regulator of p73-dependent transcription

X-H Wang
D O'Connor
G Packham
ResearchOpen Access17 Mar 2009
British Journal of Cancer

Volume: 100, P: 1347-1357
Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

M Atlas
D Head
PH Domer
Research08 Dec 1998
Leukemia

Volume: 12, P: 1895-1902
Effects of nicotinamide and carbogen on tumour oxygenation, blood flow, energetics and blood glucose levels

S P Robinson
F A Howe
J R Griffiths
ResearchOpen Access23 May 2000
British Journal of Cancer

Volume: 82, P: 2007-2014
Acute myeloid leukemia following 3M (mitoxantrone, mitomycin and methotrexate) chemotherapy for advanced breast cancer

LMA Melillo
MR Sajeva
M Carotenuto
Correspondence01 Dec 1997
Leukemia

Volume: 11, P: 2211-2213
Somatic mutations of KIT in familial testicular germ cell tumours

E A Rapley
S Hockley
M R Stratton
ResearchOpen Access18 May 2004
British Journal of Cancer

Volume: 90, P: 2397-2401
Testicular cancer

Testicular cancer, which is the most common malignancy among men between 14 and 44 years of age, has a cure rate of >90%. This Primer provides an overview of the biology, epidemiology, diagnosis and current treatment guidelines for testicular cancer, with a focus on germ cell tumours.

Liang Cheng
Peter Albers
Leendert H. J. Looijenga
Reviews05 Oct 2018
Nature Reviews Disease Primers

Volume: 4, P: 1-24
Treatment with docetaxel and cisplatin in advanced adrenocortical carcinoma, a phase II study

T Urup
W Z Pawlak
G Daugaard
ResearchOpen Access07 May 2013
British Journal of Cancer

Volume: 108, P: 1994-1997
Imaging response during therapy with radium-223 for castration-resistant prostate cancer with bone metastases—analysis of an international multicenter database

D Keizman
M O Fosboel
A Omlin
Research28 Feb 2017
Prostate Cancer and Prostatic Diseases

Volume: 20, P: 289-293
Outcome of patients with HIV-related germ cell tumours: a case–control study

T Powles
M Bower
T Oliver
ResearchOpen Access30 Mar 2004
British Journal of Cancer

Volume: 90, P: 1526-1530
11th Tuscany Retreat on Cancer Research and Apoptosis: Genetic profiling, resistance mechanisms and novel treatment concepts in cancer and neurodegeneration

Justin Pogmore
Joseph Longo
James M. Pemberton
News & ViewsOpen Access05 Dec 2019
Cell Death & Disease

Volume: 10, P: 1-3
The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation

S Castillo-Lluva
C-T Tan
A Malliri
Research21 May 2012
Oncogene

Volume: 32, P: 1735-1742
Development of a bispecific immune engager using a recombinant malaria protein

Mie A. Nordmaj
Morgan E. Roberts
Ali Salanti
ResearchOpen Access06 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-11
Second cancer risk and mortality in men treated with radiotherapy for stage I seminoma

A Horwich
S D Fossa
E Hall
ResearchOpen Access21 Nov 2013
British Journal of Cancer

Volume: 110, P: 256-263
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

Emma Scott
Kirsty Hodgson
Jennifer Munkley
ResearchOpen Access01 Feb 2023
Oncogene

Volume: 42, P: 926-937
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner

Busra Turgu
Fan Zhang
Poul H. Sorensen
ResearchOpen Access18 Feb 2021
Oncogene

Volume: 40, P: 1988-2001

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