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Leukemia (3)
Gene Therapy (3)
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Showing 1–9 of 9 results

Advanced filters: Author: M Jücker Clear advanced filters

2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist

2′-Deoxy-ADPR, formed from the combined action of NMNAT and CD38 in response to H₂O₂ signaling, activates TRPM2 ion channel currents more potently than the known agonist ADPR via a deceleration of channel inactivation and a higher average open probability.

Ralf Fliegert
Andreas Bauche
Andreas H Guse
Research26 Jun 2017
Nature Chemical Biology

Volume: 13, P: 1036-1044
Epstein–Barr virus latent membrane protein-1 activates CD25 expression in lymphoma cells involving the NFκB pathway

M Vockerodt
H Tesch
D Kube
Research04 Dec 2001
Genes & Immunity

Volume: 2, P: 433-441
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations

A Metzner
M A Horstmann
M Jücker
Research01 Feb 2007
Gene Therapy

Volume: 14, P: 699-703
Reduced proliferation of CD34⁺ cells from patients with acute myeloid leukemia after gene transfer of INPP5D

A Metzner
C Precht
M Jücker
Research15 Jan 2009
Gene Therapy

Volume: 16, P: 570-573
SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model

M Täger
S Horn
M Jücker
Research16 Nov 2017
Gene Therapy

Volume: 24, P: 749-753
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro

S Horn
J Meyer
M Jücker
Research23 Jan 2001
Leukemia

Volume: 15, P: 112-120
Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3β signaling and leads to an increased transit time through the G1 phase of the cell cycle

S Horn
E Endl
M Jücker
Research30 Sept 2004
Leukemia

Volume: 18, P: 1839-1849
Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

S Horn
U Bergholz
J Bäsecke
Research03 Mar 2008
Oncogene

Volume: 27, P: 4096-4106
Expression of a mutated form of the p85α regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO)

M Jücker
K Südel
RA Feldman
Research02 May 2002
Leukemia

Volume: 16, P: 894-901