The chemoattractant receptor GPR15 can direct CD4+ T cells to the colon. Habtezion and colleagues show that GATA-3 and Foxp3 exhibit species-specific differences in promoting GPR15 expression and thereby influences homing of CD4+ effector and regulatory T cells.
- Linh P Nguyen
- Junliang Pan
- Aida Habtezion
