Nature Search

Unexpectedly recent dates for human remains from Vogelherd

Nicholas J. Conard
Pieter M. Grootes
Fred H. Smith
Research08 Jul 2004
Nature

Volume: 430, P: 198-201
Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

IMP dehydrogenase (IMPDH) plays essential roles in purine metabolism and cell proliferation. Here Buey et al. describe a guanine nucleotides regulated molecular mechanism for allosteric communication between the regulatory and catalytic domains of IMPDH.

Rubén M. Buey
Rodrigo Ledesma-Amaro
José L. Revuelta
ResearchOpen Access12 Nov 2015
Nature Communications

Volume: 6, P: 1-11
Potent Pyrethroid Insecticides from Modified Cyclopropane Acids

M. ELLIOTT
A. W. FARNHAM
D. A. PULMAN
Research17 Aug 1973
Nature

Volume: 244, P: 456-457
Antibody to Babesia in Scottish Red Deer (Cervus elaphus)

B. M. A. LATIF
K. M. G. ADAM
Research16 Feb 1973
Nature

Volume: 241, P: 476-477
Temperature Optima for Algal Development in Yellowstone and Iceland Hot Springs

T. D. BROCK
M. LOUISE BROCK
Research12 Feb 1966
Nature

Volume: 209, P: 733-734
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

David R. Booth
Margaret Sunde
Mark B. Pepys
Research27 Feb 1997
Nature

Volume: 385, P: 787-793
The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway

Here, the authors probe the mechanism of secondary nucleation inhibition of the BRICHOS domain of the lung surfactant protein (proSP-C) against α-Syn aggregation and amyloid formation using NMR and super-resolution fluorescence microscopy.

Dhiman Ghosh
Felix Torres
Roland Riek
ResearchOpen Access20 Nov 2024
Nature Communications

Volume: 15, P: 1-15
Involvement of a gene on chromosome 9 in human fibroblast Interferon production

A. MEAGER
H. GRAVES
D. M. SWALLOW
Research01 Aug 1979
Nature

Volume: 280, P: 493-495
An intrinsic factor XII–prekallikrein-dependent pathway activates the human plasma renin–angiotensin system

F. H. M. DERKX
B. N. BOUMA
M. A. D. H. SCHALEKAMP
Research26 Jul 1979
Nature

Volume: 280, P: 315-316
A dispersive morph in the naked mole-rat

M. Justin O'Riain
Jennifer U. M. Jarvis
Chris G. Faulkes
Research18 Apr 1996
Nature

Volume: 380, P: 619-621
Regulation of α-synuclein by chaperones in mammalian cells

Chaperones interact with a canonical motif in α-synuclein, which can be prevented by phosphorylation of α-synuclein at Tyr39, whereas inhibition of this interaction leads to the localization of α-synuclein to the mitochondria and aggregate formation.

Björn M. Burmann
Juan A. Gerez
Sebastian Hiller
Research04 Dec 2019
Nature

Volume: 577, P: 127-132
Machine learning for ECG diagnosis and risk stratification of occlusion myocardial infarction

A machine learning algorithm, developed to detect occlusion myocardial infarction with no-ST elevation from electrocardiogram, outperforms clinicians in diagnostic assessments.

Salah S. Al-Zaiti
Christian Martin-Gill
Clifton W. Callaway
ResearchOpen Access29 Jun 2023
Nature Medicine

Volume: 29, P: 1804-1813
Embryonic vitamin D deficiency programs hematopoietic stem cells to induce type 2 diabetes

Environmental conditions during pregnancy contribute to offspring metabolic disease. Here, the authors show that immune cells reprogrammed in utero by maternal vitamin D deficiency increase lifetime diabetes risk in the offspring and are sufficient to transplant diabetes.

Jisu Oh
Amy E. Riek
Carlos Bernal-Mizrachi
ResearchOpen Access13 Jun 2023
Nature Communications

Volume: 14, P: 1-18
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension

Myeloid cells are involved in hypertension, but their exact role in renin-induced hypertension remains unclear. Here the authors show that impaired vitamin D signaling in myeloid cells causes hypertension via macrophage-specific miR-106b-5p secretion, which activates renin production in the kidney.

J. Oh
S. J. Matkovich
C. Bernal-Mizrachi
ResearchOpen Access23 Sept 2020
Nature Communications

Volume: 11, P: 1-12
Temporal solitons in free-space femtosecond enhancement cavities

Temporal dissipative soliton formation in a free-space femtosecond enhancement cavity with a thin Kerr medium is reported. Locking a 350-fs, 1,035-nm pulse train with a repetition rate of 100 MHz to this cavity-soliton state generates a 37-fs sech²-shaped pulse with a peak-power enhancement of 3,200.

N. Lilienfein
C. Hofer
I. Pupeza
Research21 Jan 2019
Nature Photonics

Volume: 13, P: 214-218
Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors

Tony Ngo
Andrey V. Ilatovskiy
Nicola J. Smith
Amendments and Corrections01 Mar 2021
Nature Chemical Biology

Volume: 17, P: 501
Prion (PrP^Sc)-specific epitope defined by a monoclonal antibody

C. Korth
B. Stierli
B. Oesch
Research06 Nov 1997
Nature

Volume: 390, P: 74-77
A high-quality genome sequence of Rosa chinensis to elucidate ornamental traits

A high-quality reference genome of rose is generated by sequencing a doubled haploid line. The researchers analysed the genome structure and uncovered candidate genes associated with major ornamental traits through integrated genetic and genomic analyses.

L. Hibrand Saint-Oyant
T. Ruttink
F. Foucher
ResearchOpen Access11 Jun 2018
Nature Plants

Volume: 4, P: 473-484
RETRACTED ARTICLE: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors

The ‘CoINPocket’ approach identifies pharmacological similarities between G protein–coupled receptors. On the basis of predicted pharmacological similarity to a few phylogenetically unrelated receptors, the approach identified surrogate ligands for the orphan receptor GPR37L1.

Tony Ngo
Andrey V Ilatovskiy
Nicola J Smith
Research19 Dec 2016
Nature Chemical Biology

Volume: 13, P: 235-242
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

The structures of amyloid fibres are currently primarily studied through solid state NMR and cryo-EM. Here the authors present a free-standing graphene support device that allows diffraction imaging of non-crystalline amyloid fibrils with single X-ray pulses from an X-ray free-electron laser.

Carolin Seuring
Kartik Ayyer
Henry N. Chapman
ResearchOpen Access09 May 2018
Nature Communications

Volume: 9, P: 1-10
A structural link between inactivation and block of a K⁺ channel

Christian Ader
Robert Schneider
Marc Baldus
Research18 May 2008
Nature Structural & Molecular Biology

Volume: 15, P: 605-612
Subcycle quantum electrodynamics

Few-femtosecond laser pulses are used to generate squeezed mid-infrared light transients and to detect distorted quantum fluctuations of the electric field directly in the time domain.

C. Riek
P. Sulzer
A. Leitenstorfer
Research19 Jan 2017
Nature

Volume: 541, P: 376-379
Integrated physical and transcript map of 5q31.3-qter

M Kostrzewa
BW Krings
U Müller
Research29 Jun 1998
European Journal of Human Genetics

Volume: 6, P: 266-274
Comparative shoulder kinematics during free standing, standing depression lifts and daily functional activities in persons with paraplegia: considerations for shoulder health

L M Riek
P M Ludewig
D A Nawoczenski
Research20 Nov 2007
Spinal Cord

Volume: 46, P: 335-343
In the name of the rose: a roadmap for rose research in the genome era

Marinus J. M. Smulders
Paul Arens
Fabrice Foucher
ResearchOpen Access03 May 2019
Horticulture Research

Volume: 6, P: 1-17
Transglutaminases: crosslinking enzymes with pleiotropic functions

Laszlo Lorand
Robert M. Graham
Reviews01 Feb 2003
Nature Reviews Molecular Cell Biology

Volume: 4, P: 140-156
miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells

N Kliese
P Gobrecht
C Mawrin
Research29 Oct 2012
Oncogene

Volume: 32, P: 4712-4720
Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

C R Haag
M Riek
D Ebert
Research21 Dec 2005
Heredity

Volume: 96, P: 150-158
p53 directs focused genomic responses in Drosophila

F Akdemir
A Christich
J M Abrams
Research19 Feb 2007
Oncogene

Volume: 26, P: 5184-5193

Search

Unexpectedly recent dates for human remains from Vogelherd

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

Potent Pyrethroid Insecticides from Modified Cyclopropane Acids

Antibody to Babesia in Scottish Red Deer (Cervus elaphus)

Temperature Optima for Algal Development in Yellowstone and Iceland Hot Springs

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway

Involvement of a gene on chromosome 9 in human fibroblast Interferon production

An intrinsic factor XII–prekallikrein-dependent pathway activates the human plasma renin–angiotensin system

A dispersive morph in the naked mole-rat

Regulation of α-synuclein by chaperones in mammalian cells

Machine learning for ECG diagnosis and risk stratification of occlusion myocardial infarction

Embryonic vitamin D deficiency programs hematopoietic stem cells to induce type 2 diabetes

Macrophage secretion of miR-106b-5p causes renin-dependent hypertension

Temporal solitons in free-space femtosecond enhancement cavities

Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors

Prion (PrP^Sc)-specific epitope defined by a monoclonal antibody

A high-quality genome sequence of Rosa chinensis to elucidate ornamental traits

RETRACTED ARTICLE: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors

Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

A structural link between inactivation and block of a K⁺ channel

Subcycle quantum electrodynamics

Integrated physical and transcript map of 5q31.3-qter

Comparative shoulder kinematics during free standing, standing depression lifts and daily functional activities in persons with paraplegia: considerations for shoulder health

In the name of the rose: a roadmap for rose research in the genome era

Transglutaminases: crosslinking enzymes with pleiotropic functions

miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells

Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

p53 directs focused genomic responses in Drosophila

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