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Showing 1–5 of 5 results

Advanced filters: Author: M Skirzewski Clear advanced filters

Integrating optical neuroscience tools into touchscreen operant systems

This protocol extension enables researchers to integrate optically based manipulation and measurement techniques into their touchscreen experimental systems, focusing on optogenetic manipulation, fiber photometry and microendoscopic imaging.

Patrick T. Piantadosi
Oren Princz-Lebel
Andrew Holmes
Protocols23 May 2025
Nature Protocols

Volume: 20, P: 2418-2452
Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues

Nucleus accumbens cholinergic interneurons release acetylcholine and glutamate. Here, authors show that acetylcholine, rather than glutamate, is predominantly involved in updating dopamine dynamics mediating Pavlovian approach behaviours.

Miguel Skirzewski
Oren Princz-Lebel
Timothy J. Bussey
ResearchOpen Access24 Dec 2022
Nature Communications

Volume: 13, P: 1-21
An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

A genetically encoded acetylcholine sensor with improved sensitivity allows detection of cholinergic neurotransmission in vivo in the Drosophila and mouse brain.

Miao Jing
Yuexuan Li
Yulong Li
Research28 Sept 2020
Nature Methods

Volume: 17, P: 1139-1146
ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors

M Skirzewski
I Karavanova
A Buonanno
ResearchOpen Access20 Jul 2017
Molecular Psychiatry

Volume: 23, P: 2227-2237
Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders

L Yan
A Shamir
A Buonanno
ResearchOpen Access21 Mar 2017
Molecular Psychiatry

Volume: 23, P: 1233-1243