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Showing 51–63 of 63 results

Advanced filters: Author: M van Lohuizen Clear advanced filters

The proto-oncogene Pim-1 is a target of miR-33a

M Thomas
K Lange-Grünweller
R K Hartmann
Research11 Jul 2011
Oncogene

Volume: 31, P: 918-928
Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer

K-S Lee
Y-S Lee
S-C Bae
Research15 Mar 2010
Oncogene

Volume: 29, P: 3349-3361
High-throughput insertional mutagenesis screens in mice to identify oncogenic networks

Completion of the mouse genome sequence and improved technologies for cloning and sequencing of retroviral insertions have allowed researchers to address new questions about the genes and signalling networks involved in tumour development.

Jaap Kool
Anton Berns
Reviews01 Jun 2009
Nature Reviews Cancer

Volume: 9, P: 389-399
In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation

P Taghavi
E Verhoeven
M van Lohuizen
Research01 Sept 2008
Oncogene

Volume: 27, P: 6806-6816
The field of cancer research: an indicator of present transformations in biology

M Morange
Reviews23 Jul 2007
Oncogene

Volume: 26, P: 7607-7610
ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia

E Canaani
T Nakamura
A Mazo
ReviewsOpen Access17 Feb 2004
British Journal of Cancer

Volume: 90, P: 756-760
The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

Proteomic and genomic analysis of Polycomb group complexes in embryonic stem cells and neural progenitor cells identifies new PRC1 and PRC2 interaction partners and targets during neural lineage commitment.

Susan L Kloet
Matthew M Makowski
Michiel Vermeulen
Research13 Jun 2016
Nature Structural & Molecular Biology

Volume: 23, P: 682-690
CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development

Christopher Walsh and colleagues identify mutations in CHMP1A in human cerebellar hypoplasia and microcephaly. Cells lacking CHMP1A show decreased cell proliferation and decreased expression of BMI1, a negative regulator of stem cell proliferation.

Ganeshwaran H Mochida
Vijay S Ganesh
Christopher A Walsh
Research30 Sept 2012
Nature Genetics

Volume: 44, P: 1260-1264
Soft skills turned into hard facts: nucleosome remodelling at developmental switches

M Chioda
P B Becker
Reviews07 Apr 2010
Heredity

Volume: 105, P: 71-79
MYC oncogenes and human neoplastic disease

Chadd E Nesbit
Jean M Tersak
Edward V Prochownik
Reviews13 May 1999
Oncogene

Volume: 18, P: 3004-3016
KLF4, p21 and context-dependent opposing forces in cancer

Krüppel-like factors are transcriptional regulators that function both as tumour suppressors and oncogenes through their control of p21 expression. This might be an important nodal point of cell control for other factors that have opposing functions in cancer.

Benjamin D. Rowland
Daniel S. Peeper
Reviews22 Dec 2005
Nature Reviews Cancer

Volume: 6, P: 11-23
Context-dependent actions of Polycomb repressors in cancer

M Koppens
M van Lohuizen
Reviews08 Jun 2015
Oncogene

Volume: 35, P: 1341-1352
Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells

J Yuan
M Takeuchi
A Iwama
Research29 Apr 2011
Leukemia

Volume: 25, P: 1335-1343