The CATERPILLER family of proteins, like the mammalian Toll-like receptors, are sensors of microbial products and regulators of the immune reponse. Genetic defects in CATERPILLER genes are associated with various immunological disorders, including hereditary periodic fevers, indicating that CATERPILLERs are important in regulating inflammatory responses.
- Jenny P.-Y. Ting
- Daniel L. Kastner
- Hal M. Hoffman
